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. 2025 Jul 31;12(8):719.
doi: 10.3390/vetsci12080719.

Individual Genomic Loci, Transcript Levels, and Serum Profiles of Immune and Antioxidant Markers Associated with Bacteria-Induced Abortion in Sheep (Ovis aries)

Attia Eissa  1 , Ahmed A Elsayed  2 , Amin Tahoun  3   4 , Adel M El-Kattan  2 , Islam M Wassif  2 , Amani A Hafez  2 , Ragab Mohamed  5 , Ahmed I Ateya  6 , Hanan M Alharbi  7 , Khairiah M Alwutayd  7 , Aiman A Ammari  8 , Manal A Babaker  9 , Mansour A Alghamdi  10   11 , Torsten Bohn  12 , Ammar Al-Farga  13 , Hossam M Aljawdah  14
Affiliations

Individual Genomic Loci, Transcript Levels, and Serum Profiles of Immune and Antioxidant Markers Associated with Bacteria-Induced Abortion in Sheep (Ovis aries)

Attia Eissa et al. Vet Sci. .

Abstract

Aboudeleik sheep are a prominent native breed in desert and semi-desert areas, known for their adaptability to harsh climates and their utility in both milk and meat production [...].

Keywords: abortion and sheep; antioxidants; gene expression; immunity; single-nucleotide polymorphisms.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
(A–C) Electrophoresis analysis of PCR product of amplified (A) Brucella melitensis, (B) Salmonella spp., and (C) Campylobacter spp. (A) Lanes 1, 2, 3, and 5 indicate a positive amplification of Brucella melitensis at the 839 bp, (B) Lanes 1, 2, and 4 indicate positive amplification of Salmonella at the 284 bp, and (C) all samples indicate positive amplification at 650 bp for Campylobacter.
Figure 2
Figure 2
(A–D) Electrophoresis analysis of PCR product of amplified (A) Coxiella burnetii, (B) Chlamydia psittaci, (C) Listeria monocytogens, and (D) Leptospira. All sample negative for all bacteria at 687, 300, 1200 and 202 bp, respectively.
Figure 3
Figure 3
Comparative analysis of immune-related genes in normal and abortion-affected ewes. Values are mean ± SE. The symbol * denotes statistical significance (* p < 0.05).
Figure 4
Figure 4
Comparative analysis of antioxidant gene expression in healthy and abortion-affected ewes. Values are mean ± SE. Asterisks (*) indicate statistically significant differences (* p < 0.05).
See this image and copyright information in PMC

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