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Review
. 2025 Jul 28;13(8):798.
doi: 10.3390/vaccines13080798.

Optimizing Immunization Strategies for Individuals Living with HIV: A Review of Essential Vaccines, Vaccine Coverage, and Adherence Factors

Lina M Würfel  1   2   3 , Anja Potthoff  1   2   3 , Adriane Skaletz-Rorowski  1   2 , Sandeep Nambiar  1   2 , Nessr Abu Rached  3
Affiliations
Review

Optimizing Immunization Strategies for Individuals Living with HIV: A Review of Essential Vaccines, Vaccine Coverage, and Adherence Factors

Lina M Würfel et al. Vaccines (Basel). .

Abstract

Human immunodeficiency virus (HIV) infection remains a major challenge in global health. In recent years, vaccines have emerged as an important tool for the treatment and prevention of HIV-related complications. This review article addresses the evolving landscape of vaccines for people living with HIV (PLWH), evaluating current vaccination strategies for standard vaccines and travel vaccines in PLWH compared to the general population and offering a summary of the current recommended vaccines. It evaluates studies for vaccine effectiveness and safety and discusses methods to improve vaccination rates among PLWH. Systematic research was carried out using keywords. We address the current state of knowledge and highlight areas for future research and development.

Keywords: HIV; PLWH; immunity; immunodeficiency; review; vaccine recommendations; vaccines.

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Conflict of interest statement

The authors declare no conflicts of interest.

References

    1. Birk N.K., Monday L., Singh T., Cherabuddi M., Hojeij M., Ho B., Chen A., Brar I., Alangaden G. Vaccine coverage and factors associated with vaccine adherence in persons with HIV at an urban infectious disease clinic. Hum. Vaccines Immunother. 2023;19:2204785. doi: 10.1080/21645515.2023.2204785. - DOI - PMC - PubMed
    1. Johnson T.M., Klepser D.G., Bares S.H., Scarsi K.K. Predictors of vaccination rates in people living with HIV followed at a specialty care clinic. Hum. Vaccines Immunother. 2021;17:791–796. doi: 10.1080/21645515.2020.1802163. - DOI - PMC - PubMed
    1. Tsachouridou O., Georgiou A., Naoum S., Vasdeki D., Papagianni M., Kotoreni G., Forozidou E., Tsoukra P., Gogou C., Chatzidimitriou D., et al. Factors associated with poor adherence to vaccination against hepatitis viruses, streptococcus pneumoniae and seasonal influenza in HIV-infected adults. Hum. Vaccines Immunother. 2019;15:295–304. doi: 10.1080/21645515.2018.1509644. - DOI - PMC - PubMed
    1. BreiBreitschwerdt S., Schwarze-Zander C., Al Tayy A., Mutevelli J., Wasmuth J.-C., Rockstroh J.K., Boesecke C. Implementation of EACS vaccination recommendations among people living with HIV. Infection. 2022;50:1491–1497. doi: 10.1007/s15010-022-01827-6. - DOI - PMC - PubMed
    1. Dirschka T., Oster-Schmidt C., Schmitz L., editors. Klinikleitfaden Dermatologie. 4th ed. Elsevier; Amsterdam, The Netherlands: 2020.

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