Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Published Erratum
. 2025 Sep 2;122(35):e2521789122.
doi: 10.1073/pnas.2521789122. Epub 2025 Aug 28.

Correction for Soni et al., BIK polymorphism and proteasome regulation unveil host risk factor for severe influenza

No authors listed
Published Erratum

Correction for Soni et al., BIK polymorphism and proteasome regulation unveil host risk factor for severe influenza

No authors listed. Proc Natl Acad Sci U S A. .
No abstract available

PubMed Disclaimer

Figures

Fig. 4.
Fig. 4.
IRF1 silencing upregulates BIK, promoting viral replication and inflammation. NHBEs with the GG variant of the BIK SNP (NHBEG/G) were transfected with siControl or siIRF1 followed by infection with 0.1 MOI Cal/09 48 h posttransfection. (A) Protein lysates were analyzed for BIK, Bim, Bax, Bak, and IRF1 levels. (B) Viral titers and (C) inflammatory cytokine and chemokine levels in cell supernatants were compared at 72 hpi using TCID50 assay and Luminex multiplex assay, respectively. t test; n = 6/group. Error bars: Mean ± SEM.
Fig. 7.
Fig. 7.
β5 protects mice from IAV-induced morbidity and mortality. WT C57BL/6 mice were instilled intranasally with 1011 GC of AAV6.2-EGFP or AAV6.2-β5. Mice were infected with 250 pfu PR/8 on day 5 post-AAV treatment. On day 5 post PR/8 infection, (A) paraffin-embedded lung tissues were immunostained for EGFP or β5 and analyzed using fluorescent microscopy and (B) lung viral load was measured using TCID50 assay. (C and D) Mice were weighed daily and monitored for survival over a period of 14 dpi. n = 10 to 13/group, *P < 0.05. (E) Inflammatory cytokine and chemokine levels in the lung homogenates analyzed at 5 dpi using Luminex multiplex assay. t test; n = 4-10/group. Error bars: Mean ± SEM.
See this image and copyright information in PMC

Erratum for

  • BIK polymorphism and proteasome regulation unveil host risk factor for severe influenza.
    Soni S, Yildiz S, Allen EK, Petersen H, Peeples M, El Zahed S, Rosas L, Anang V, Antonescu L, Nho RS, Mora AL, Horowitz JC, Rojas M, Medina RA, Thomas PG, García-Sastre A, Tesfaigzi Y, Mebratu YA. Soni S, et al. Proc Natl Acad Sci U S A. 2025 Jul 15;122(28):e2424367122. doi: 10.1073/pnas.2424367122. Epub 2025 Jul 8. Proc Natl Acad Sci U S A. 2025. PMID: 40627391 Free PMC article.

Publication types

LinkOut - more resources