Advancing comparative placentation through spatial transcriptomics and organoid models
- PMID: 40880314
- PMCID: PMC12396701
- DOI: 10.1371/journal.pbio.3003346
Advancing comparative placentation through spatial transcriptomics and organoid models
Abstract
The placenta is one of the most diverse organs among eutherian mammals, and comparative placentation studies can reveal fundamental processes that support a successful pregnancy. A new study in PLOS Biology uses swine placental organoids and in vivo spatial transcriptomics to uncover key insights into placental cell diversity and evolution.
Copyright: © 2025 Francesca Soncin. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Conflict of interest statement
The author has declared that no competing interests exist.
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Comment on
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Defining cellular diversity at the swine maternal-fetal interface using spatial transcriptomics and organoids.PLoS Biol. 2025 Aug 28;23(8):e3003302. doi: 10.1371/journal.pbio.3003302. eCollection 2025 Aug. PLoS Biol. 2025. PMID: 40875599 Free PMC article.
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