The authors reply

Samuel Heuts^{1

2}, Andrea Gabrio³, Julia Bels⁴, Dieter Mesotten^{5

6}, Marcel van de Poll^{4

7

8}

Affiliations

¹ Department of Cardiothoracic Surgery, Maastricht University Medical Center (MUMC+), Maastricht, The Netherlands.
² Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.
³ Department of Statistics and Methodology, Maastricht University, Maastricht, The Netherlands.
⁴ Department of Intensive Care Medicine, Maastricht University Medical Center (MUMC+), Maastricht, The Netherlands.
⁵ Department of Intensive Care Medicine, Ziekenhuis Oost-Limburg, Genk, Belgium.
⁶ UHasselt, Faculty of Medicine and Life Sciences, Diepenbeek, Belgium.
⁷ School for Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Maastricht, The Netherlands.
⁸ Department of Surgery, Maastricht University Medical Center (MUMC+), Maastricht, The Netherlands.

Samuel Heuts et al. Crit Care Med. 2025.

. 2025 Sep 1;53(9):e1857-e1858.

doi: 10.1097/CCM.0000000000006779. Epub 2025 Sep 2.

Samuel Heuts^{1

2}, Andrea Gabrio³, Julia Bels⁴, Dieter Mesotten^{5

6}, Marcel van de Poll^{4

7

8}

¹ Department of Cardiothoracic Surgery, Maastricht University Medical Center (MUMC+), Maastricht, The Netherlands.
² Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.
³ Department of Statistics and Methodology, Maastricht University, Maastricht, The Netherlands.
⁴ Department of Intensive Care Medicine, Maastricht University Medical Center (MUMC+), Maastricht, The Netherlands.
⁵ Department of Intensive Care Medicine, Ziekenhuis Oost-Limburg, Genk, Belgium.
⁶ UHasselt, Faculty of Medicine and Life Sciences, Diepenbeek, Belgium.
⁷ School for Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Maastricht, The Netherlands.
⁸ Department of Surgery, Maastricht University Medical Center (MUMC+), Maastricht, The Netherlands.

No abstract available

Conflict of interest statement

The authors have disclosed that they do not have any potential conflicts of interest.

1. Pereira TV, Mazer CD, Teja B: Bayesian probabilities and thresholds in meta-analyses and randomized trials in critical care research. Crit Care Med 2025; 53:e1855–e1856
1. Heuts S, Lee Z-Y, Lew CCH, et al.: Higher versus lower protein delivery in critically ill patients: A systematic review and bayesian meta-analysis. Crit Care Med 2025; 53:e645–e655
1. Heuts S, Kawczynski MJ, Sayed A, et al.: Bayesian analytical methods in cardiovascular clinical trials: Why, when, and how. Can J Cardiol 2025; 41:30–44
1. Zampieri FG, Casey JD, Shankar-Hari M, et al.: Using Bayesian methods to augment the interpretation of critical care trials. An overview of theory and example reanalysis of the alveolar recruitment for acute respiratory distress syndrome trial. Am J Respir Crit Care Med 2021; 203:543–552
1. Heuts S, Kawczynski MJ, Velders BJJ, et al.: Statistical primer: An introduction into the principles of Bayesian statistical analyses in clinical trials. Eur J Cardiothorac Surg 2025; 67:ezaf139