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. 2025 Sep 1;15(9):8717-8721.
doi: 10.21037/qims-2025-760. Epub 2025 Aug 12.

Late-onset familial cerebral cavernous malformation without a family history: a case description

Zhuangzhuang Zhang  1   2 , Weiping Sun  1   2 , Zhaoxia Wang  1   2 , Luhua Wei  1   2
Affiliations

Late-onset familial cerebral cavernous malformation without a family history: a case description

Zhuangzhuang Zhang et al. Quant Imaging Med Surg. .
No abstract available

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Conflict of interest statement

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://qims.amegroups.com/article/view/10.21037/qims-2025-760/coif). The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Brain MRI showed multiple cerebral cavernous malformations. Brain MRI revealed a Zabramski Type II lesion (arrows) adjacent to the left lateral ventricle, characterized by a mixed signal on (A) T1-weighted and (B) T2-weighted FLAIR imaging, along with marked hypointensity on SWI (C). Additionally, multiple Zabramski Type IV lesions (arrowheads) were observed in the (A-C) bilateral frontal and parietal lobes, periventricular region, and (D-F) pons, characterized by significant hemosiderin deposition; this was not visible on (A,D) T1-weighted or (B,E) T2-weighted FLAIR imaging but was distinctly visible on (C,F) SWI. FLAIR, fluid-attenuated inversion recovery; MRI, magnetic resonance imaging; SWI, susceptibility-weighted imaging.
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