Empagliflozin for non-diabetic metabolic dysfunction-associated steatotic liver disease: a promising therapeutic agent in transition
- PMID: 40893754
- PMCID: PMC12393100
- DOI: 10.21037/hbsn-2025-250
Empagliflozin for non-diabetic metabolic dysfunction-associated steatotic liver disease: a promising therapeutic agent in transition
Keywords: Liver; empagliflozin; magnetic resonance imaging-proton density fat fraction (MRI-PDFF); metabolic dysfunction-associated steatotic liver disease (MASLD); sodium-glucose co-transporter-2 (SGLT2).
Conflict of interest statement
Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://hbsn.amegroups.com/article/view/10.21037/hbsn-2025-250/coif). S.S.L. reports consulting fees from Abbvie, Gilead, Mallinckrodt, Grifols, and Jazz; honoraria from Abbvie and Gilead; participation on Data Safety Monitoring Boards for Abbvie and Jazz; and stock options in Oncoustics Corp. The other authors have no conflicts of interest to declare.
Comment on
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Effects of empagliflozin on liver fat in patients with metabolic dysfunction-associated steatotic liver disease without diabetes mellitus: A randomized, double-blind, placebo-controlled trial.Hepatology. 2024 Oct 1;80(4):916-927. doi: 10.1097/HEP.0000000000000855. Epub 2024 Mar 27. Hepatology. 2024. PMID: 38536017 Clinical Trial.
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