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Case Reports
. 2025 Aug 14:15:1645306.
doi: 10.3389/fonc.2025.1645306. eCollection 2025.

Mucinous adenocarcinoma of the prostate with extremely low prostate-specific antigen levels, recurrent disease: a case report

Xu Yu  1 , Jie Yuan  1 , Zhiming Wang  2 , Niannian Wang  2 , Xiangfei He  2 , Jie Liu  2
Affiliations
Case Reports

Mucinous adenocarcinoma of the prostate with extremely low prostate-specific antigen levels, recurrent disease: a case report

Xu Yu et al. Front Oncol. .

Abstract

Mucinous adenocarcinoma (MC) is a very rare type of prostate cancer, accounting for less than 1% of prostate adenocarcinomas, and its etiology is still unclear. Its clinical symptoms are similar to those of prostate hyperplasia and follicular carcinoma of the prostate, which are often misdiagnosed, and a definite diagnosis depends on pathological diagnosis, and the secretion of a large amount of mucus is its pathological characteristic. Surgery and endocrine therapy are the main treatment modalities, followed by radiation therapy and comprehensive therapy. Since this disease is rarely reported, in order to improve the understanding and diagnosis of clinically rare MC, we report a case of primary recurrent mucinous adenocarcinoma of the prostate and analyze its clinical features, pathological diagnosis, treatment and prognosis in the light of the literature.

Keywords: case report; mucinous adenocarcinoma; pathology; prostate cancer; therapy.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Adenocarcinoma (adenoidal arrangement of cancer cells).
Figure 2
Figure 2
Prostate MRI (scanning)+prostate adenocarcinoma with mucinous carcinoma differentiation (cancer cells arranged in adenoid pattern and rich in mucus).
Figure 3
Figure 3
MRI of the prostate+the extraperitoneal mass was adenocarcinoma.
See this image and copyright information in PMC

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