Addendum: Retinoic acid signaling is critical during the totipotency window in early mammalian development

Ane Iturbide¹, Mayra L Ruiz Tejada Segura^#^{1

2

3}, Camille Noll^#¹, Kenji Schorpp^#⁴, Ina Rothenaigner⁴, Elias R Ruiz-Morales^{1

5}, Gabriele Lubatti^{1

2

3}, Ahmed Agami¹, Kamyar Hadian⁴, Antonio Scialdone^{1

2

3}, Maria-Elena Torres-Padilla^{6

7}

Affiliations

¹ Institute of Epigenetics and Stem Cells (IES), Helmholtz Zentrum München, Munich, Germany.
² Institute of Functional Epigenetics (IFE), Helmholtz Zentrum München, Neuherberg, Germany.
³ Institute of Computational Biology (ICB), Helmholtz Zentrum München, Neuherberg, Germany.
⁴ Assay Development & Screening Platform, Institute of Molecular Toxicology & Pharmacology (TOXI), Helmholtz Zentrum München, Neuherberg, Germany.
⁵ Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
⁶ Institute of Epigenetics and Stem Cells (IES), Helmholtz Zentrum München, Munich, Germany. torres-padilla@helmholtz-muenchen.de.
⁷ Faculty of Biology, Ludwig-Maximilians Universität, Munich, Germany. torres-padilla@helmholtz-muenchen.de.

^# Contributed equally.

Ane Iturbide et al. Nat Struct Mol Biol. 2025.

. 2025 Sep 2.

doi: 10.1038/s41594-025-01661-y. Online ahead of print.

¹ Institute of Epigenetics and Stem Cells (IES), Helmholtz Zentrum München, Munich, Germany.
² Institute of Functional Epigenetics (IFE), Helmholtz Zentrum München, Neuherberg, Germany.
³ Institute of Computational Biology (ICB), Helmholtz Zentrum München, Neuherberg, Germany.
⁴ Assay Development & Screening Platform, Institute of Molecular Toxicology & Pharmacology (TOXI), Helmholtz Zentrum München, Neuherberg, Germany.
⁵ Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
⁶ Institute of Epigenetics and Stem Cells (IES), Helmholtz Zentrum München, Munich, Germany. torres-padilla@helmholtz-muenchen.de.
⁷ Faculty of Biology, Ludwig-Maximilians Universität, Munich, Germany. torres-padilla@helmholtz-muenchen.de.

^# Contributed equally.

No abstract available

References

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