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. 2025 Sep 3:1-9.
doi: 10.1080/17581869.2025.2552633. Online ahead of print.

Superficial and deep cervical plexus blocks versus patient-controlled analgesia in total laryngectomy; a randomized trial

Affiliations

Superficial and deep cervical plexus blocks versus patient-controlled analgesia in total laryngectomy; a randomized trial

Nourhan Mohamed Elsherbiny et al. Pain Manag. .

Abstract

Introduction: The cervical plexus block (CPB) delivers analgesia for surgeries in the head and neck . Patient-controlled analgesia (PCA) has been utilized to enhance pain management. This study evaluates combined bilateral superficial and deep CPB versus PCA in postoperative pain management after total laryngectomy.

Materials and methods: Randimized two equal groups: the CPB group (n = 25), who received combined bilateral US-guided superficial and deep CBP, and the PCA group (n = 25), who received PCA. The primary outcome was postoperative visual analog scale (VAS) . The secondary outcomes were hemodynamic changes, fentanyl consumption, first rescue analgesia, hospital stay, and postoperative complications.

Results: Postoperative VAS scores (at 2 and 4 h) were greater in the PCA group compared to the CPB group, p values (0.031, 0.044), respectively. The results were comparable at 6 and 12 h; while at 18 and 24 h, they were elevated in the CPB. The intraoperative hemodynamics were elevated in the PCA group at skin incision and after 30 min. Fentanyl consumption, first rescue analgesia, hospital stay, and postoperative complications were comparable.

Conclusion: Ultrasound-guided combined bilateral superficial and deep CPB provided superior analgesia in the early postoperative period compared to PCA.

Clinical trial registration: https://pactr.samrc.ac.za PACTR202403682323400.

Keywords: Patient-controlled analgesia; deep cervical plexus block; head and neck surgeries; superficial cervical plexus block; total laryngectomy.

Plain language summary

This study evaluates the effectiveness of block of nerves in the neck versus intravenous injection of pain-relieving drugs controlled by the patient himself in patients with cancer of the upper part of the airway undergoing surgery for excision. A nerve block is an injection of anesthetic into or around a specific nerve or group of nerves to numb an area of the body, either for surgery or to manage pain. Patients were randomly assigned to two equal groups (with 25 patients in each group). One group received a cervical plexus block (CPB, a nerve block of nerve bundles in the neck). The other group received painkillers through a device that automatically delivers the drug into the patients vein – the device was controlled by the patients themselves, known as patient-controlled analgesia (PCA). Pain levels were measured at 2, 4, 6, 12, 18, and 24 h after the surgery. Changes in heartbeat and blood pressure, total use of pain killer drugs, first time patient asked for drugs to relieve pain, days spent in the hospital, and problems after surgery were also measured. Results showed that patient-controlled analgesia provided a less unpleasant feeling, a sign from your nerves that something may be wrong, than cervical plexus block. Changes in heartbeat and blood pressure were greater than in the patient-controlled analgesia group, after making a small cut to the skin with a scalpel and after waiting for 30 min.

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