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. 2025 Aug 18:13:1634232.
doi: 10.3389/fped.2025.1634232. eCollection 2025.

Sound waves of progress: advancing endoscopic ultrasound in pediatric gastroenterology

Sumith Roy  1 , Rachel Gitter  2 , Jennifer Nguyen  3 , Andrew Huang  4 , Clifton Huang  1   2   5
Affiliations

Sound waves of progress: advancing endoscopic ultrasound in pediatric gastroenterology

Sumith Roy et al. Front Pediatr. .

Abstract

Introduction: A substantial body of research validates the application of endoscopic ultrasound in adults in the management of biliary and pancreatic conditions. There is limited data regarding its impact on children, although its use has steadily increased over the years. This study aims to assess long-term data on indications, efficacy and safety of endoscopic ultrasound in pediatric patients.

Methods: This ambispective registry data reflects a single-center experience of endoscopic ultrasound either as a stand-alone procedure, or in conjunction with guided interventions such as lumen-apposing metal stents or as a pre-assessment tool prior to other interventions such as endoscopic retrograde cholangiopancreatography, both of which were independently performed by a pediatric gastroenterologist.

Results: A total of 294 EUS were performed in 216 patients (55.1% female, median age (IQR) 15 [11.9-16.9] years). Technical success was 100% and no complications were associated with EUS.

Discussion: This robust dataset adds to the emerging evidence of EUS performed with a high technical success rate coupled with low risk for adverse events.

Keywords: EUS; choledocholithiasis; endoscopic ultrasound (EUS); linear EUS; pediatric gastroenterologist; radial EUS.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Endoscopic ultrasound (EUS) demonstrating absence of choledocholithiasis, averting endoscopic retrograde cholangiopancreatography (ERCP).
Figure 2
Figure 2
(A) Esophageal wall thickness prior to IL-4Rα antibody treatment. (B) Elastography demonstrating concerns for esophageal wall stiffness.
Figure 3
Figure 3
Rectal EUS showing an abscess and fistula at the 12'o clock position.
Figure 4
Figure 4
Computed tomography (CT) abdomen demonstrating a pancreatic pseudocyst (indicated by the yellow arrow).
Figure 5
Figure 5
(A) Linear EUS during placement of lumen-apposing metal stent (LAMS). (B) Endosopic view post-LAMS placement.
Figure 6
Figure 6
CT chest confirming a short-segment esophageal stricture.
Figure 7
Figure 7
Esophagogastroduodenoscopy (EGD) with EUS miniprobe positioned for high-resolution imaging of the esophageal layers.
Figure 8
Figure 8
EUS showing axial sections of esophageal layer thickness and potential area of fibrosis.
Figure 9
Figure 9
EUS-guided liver biopsy (left) and post-biopsy under Doppler imaging (right).
See this image and copyright information in PMC

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