Comment on

• Which Benefits Can Justify Risks in Research?

  van Rijssel TI, van Thiel GJMW, Gardarsdottir H, van Delden JJM; Trials@Home consortium. van Rijssel TI, et al. Am J Bioeth. 2025 May;25(5):65-75. doi: 10.1080/15265161.2023.2296404. Epub 2024 Jan 5. Am J Bioeth. 2025. PMID: 38181217
• Benefits that Offset Research Risks and Burdens are Qualitatively Different.

  Gelinas L, Silverman BC, Bierer BE. Gelinas L, et al. Am J Bioeth. 2025 May;25(5):78-80. doi: 10.1080/15265161.2025.2488293. Epub 2025 May 8. Am J Bioeth. 2025. PMID: 40339066 No abstract available.
• Data Safety Monitoring and Collateral Benefits in Decentralized Trials.

  Barnbaum DR. Barnbaum DR. Am J Bioeth. 2025 May;25(5):101-103. doi: 10.1080/15265161.2025.2488265. Epub 2025 May 8. Am J Bioeth. 2025. PMID: 40339067 No abstract available.
• Considering Third-Party and Relational Benefits in Research Risk-Benefit Analyses.

  Kraft SA, Saylor KW. Kraft SA, et al. Am J Bioeth. 2025 May;25(5):95-97. doi: 10.1080/15265161.2025.2488266. Epub 2025 May 8. Am J Bioeth. 2025. PMID: 40339069 No abstract available.
• Decentralized Trials: Let's Not Overthink It.

  Schaefer GO, Muyskens K, Teo I, Menikoff J. Schaefer GO, et al. Am J Bioeth. 2025 May;25(5):89-91. doi: 10.1080/15265161.2025.2488268. Epub 2025 May 8. Am J Bioeth. 2025. PMID: 40339070 No abstract available.
• Acceptable Risks or Negotiable Ethics? The Dilemma of Collateral Benefits in Clinical Research.

  Assis de Jesus Junior S, Fernandes de Aguiar D. Assis de Jesus Junior S, et al. Am J Bioeth. 2025 May;25(5):103-105. doi: 10.1080/15265161.2025.2488261. Epub 2025 May 8. Am J Bioeth. 2025. PMID: 40339072 No abstract available.
• Research Payments, Other Collateral Benefits, and the Ethics of Imposing Research Risk.

  Różyńska JK. Różyńska JK. Am J Bioeth. 2025 May;25(5):92-94. doi: 10.1080/15265161.2025.2488286. Epub 2025 May 8. Am J Bioeth. 2025. PMID: 40339074 No abstract available.
• Racing to the Bottom: Adam Smith's Hazard Pay Does Not Justify Compensation for Research Risks.

  Shrader-Frechette KS. Shrader-Frechette KS. Am J Bioeth. 2025 May;25(5):98-100. doi: 10.1080/15265161.2025.2488254. Epub 2025 May 8. Am J Bioeth. 2025. PMID: 40339082 No abstract available.
• Including Collateral Benefits? Beware of Therapeutic Misconception!

  Tromp K, Bunnik EM. Tromp K, et al. Am J Bioeth. 2025 May;25(5):83-86. doi: 10.1080/15265161.2025.2488255. Epub 2025 May 8. Am J Bioeth. 2025. PMID: 40339084 No abstract available.
• Accurately Understanding the Potential Benefits of Decentralized Clinical Trials.

  Sugarman J, Vayena E. Sugarman J, et al. Am J Bioeth. 2025 May;25(5):81-83. doi: 10.1080/15265161.2025.2488257. Epub 2025 May 8. Am J Bioeth. 2025. PMID: 40339090 No abstract available.
• Which Risks Can Undermine Benefits in Research?

  Chen SS, Brenna CTA, Mollen J, Das S. Chen SS, et al. Am J Bioeth. 2025 May;25(5):86-88. doi: 10.1080/15265161.2025.2488270. Epub 2025 May 8. Am J Bioeth. 2025. PMID: 40339095 No abstract available.
• A Solution without a Problem.

  Pan S, Chattopadhyay A, Taylor HA. Pan S, et al. Am J Bioeth. 2025 May;25(5):76-77. doi: 10.1080/15265161.2025.2488275. Epub 2025 May 8. Am J Bioeth. 2025. PMID: 40339100 No abstract available.