Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Jun 26;8(5):445-448.
doi: 10.1002/iju5.70061. eCollection 2025 Sep.

Multiple Angiolipomas of the Spermatic Cord: A Case Report

Kazune Teshima  1 , Tomoaki Hakariya  1 , Daiyu Aoki  1 , Naoki Nishimura  1 , Shunsuke Sato  2 , Masahiro Nakashima  3
Affiliations

Multiple Angiolipomas of the Spermatic Cord: A Case Report

Kazune Teshima et al. IJU Case Rep. .

Abstract

Introduction: We report a rare case of multiple spermatic cord angiolipomas.

Case presentation: An 85-year-old man with a history of laparoscopic right nephrectomy for renal cell carcinoma was referred for evaluation of a palpable right scrotal mass. Ultrasonography showed a single solid mass. Computed tomography and magnetic resonance imaging revealed a solid nodule in contact with the right spermatic cord and a fatty mass below the nodule. Right inguinal orchiectomy was performed. Histopathological examination of the surgical specimen was consistent with angiolipoma. He was discharged 4 days postoperatively, and no recurrence has been observed during the subsequent 8 months.

Conclusion: Angiolipomas are benign and rarely occur in paratesticular tissue. They should be distinguished from liposarcomas, given the differences in treatment and prognosis. Diagnosis requires surgical resection and histopathological examination. Once resected, angiolipomas rarely recur, and the prognosis is good.

Keywords: angiolipoma; paratesticular; scrotum; spermatic cord.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflicts of interest.

Figures

FIGURE 1
FIGURE 1
Computed tomography showed a 1.5 cm nodular mass adjacent to the spermatic vein (white arrow) and a 4.7 cm mass with heterogeneous signal density above the normal right testis (black arrow).
FIGURE 2
FIGURE 2
(A) T2‐weighted imaging showed a cephalad nodule with low signal intensity (white arrow) and a mass with heterogenous signal intensity caudally (black arrow). (B) Short tau inversion recovery imaging showed high signal intensity in portions of both (arrow). (C) Apparent diffusion coefficient mapping did not show low signal intensity. Differences in the distribution of the adipose component could have resulted in inhomogeneous signal intensity.
FIGURE 3
FIGURE 3
(A) Grossly, three lesions were observed (arrows). (B) Fibrotic stromal component. (C) Mature adipose tissue and blood vessels of various size. In the largest lesion, (D) Immunostaining for α‐smooth muscle actin in the vessel walls was positive. (E) Staining for S‐100 was positive. (F) Staining for human melanin black‐45 was negative.
See this image and copyright information in PMC

References

    1. Mizoguchi K., Okido M., Akamine S., and Yoneda R., “Angiolipoma of the Breast–A Case Report,” Journal of Japan Surgical Association 83 (2022): 1009–1012.
    1. Kalyvas V., Gkekas C., Papadopoulos D., et al., “Intratesticular Angiolipoma: A Rare Case of Adipose Tissue Presence in the Testis,” Case Reports in Urology 2019 (2019): 7606530, 10.1155/2019/7606530. - DOI - PMC - PubMed
    1. Kransdorf M. J., Larsen B. T., Goulding K. A., Cumsky J. L., Hwang S., and Long J. R., “Angiolipoma: A Review of 778 Lesions in 344 Patients,” Skeletal Radiology 52 (2023): 541–552. - PubMed
    1. Srivastava A., Gupta N., Joice G. A., and Wright E. J., “Management and Excision of a 15 Cm Paratesticular Angiolipoma,” Urology Case Reports 15 (2016): 8–10. - PMC - PubMed
    1. Li S. L., Zhang J. W., Wu Y. Q., Lu K. S., Zhu P., and Wang X. W., “Subcutaneous Angiolipoma in the Scrotum: A Case Report,” World Journal of Clinical Cases 9 (2021): 7954–7958. - PMC - PubMed

LinkOut - more resources