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Observational Study
. 2025 Sep 11;14(9):piaf080.
doi: 10.1093/jpids/piaf080.

Early Antibiotic Discontinuation in Pediatric Suspected Septic Arthritis With No Pathogen Identified: Results of a 6-Year Protocol-Based Observational Study

Yannis Lassoued  1 , Cindy Mallet  2 , Philippe Bidet  3 , Juliette Goutines  1 , Jeanne Truong  1 , Maud Gits  3 , Brice Ilharreborde  2 , Stéphane Bonacorsi  3   4 , Anne-Laure Simon  2 , Marion Caseris  1
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Observational Study

Early Antibiotic Discontinuation in Pediatric Suspected Septic Arthritis With No Pathogen Identified: Results of a 6-Year Protocol-Based Observational Study

Yannis Lassoued et al. J Pediatric Infect Dis Soc. .

Abstract

In a 6-year observational study of 45 children with suspected septic arthritis and no pathogen identified, early antibiotic discontinuation based on strict clinical and biological criteria was not associated with relapse during the 6-month period following hospitalization, supporting this approach may be safe and reduce unnecessary antibiotic exposure.

Keywords: antibiotic discontinuation; antibiotic stewardship; bone and joint infections in children; molecular diagnostics; presumed septic arthritis.

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