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. 2025 Sep 5:S0091-6749(25)00859-0.
doi: 10.1016/j.jaci.2025.08.001. Online ahead of print.

Anifrolumab treatment of Singleton-Merten syndrome 2 due to a novel RIGI variant

Evan E Hsu  1 , Courtney E LeSon  1 , Michael T Lam  1 , Seigo Okada  2 , Jian Yue  3 , Casey A Rimland  4 , Rachel Weng  1 , Qing Zhou  5 , Tal Geva  6 , Amy E Roberts  7 , Charmaine Ilagan  8 , Chrystalle Katte Carreon  8 , Mary Beth F Son  1 , Pui Y Lee  9
Affiliations

Anifrolumab treatment of Singleton-Merten syndrome 2 due to a novel RIGI variant

Evan E Hsu et al. J Allergy Clin Immunol. .
No abstract available

Keywords: RIG-I/RIGI; Singleton-Merten syndrome; anifrolumab; type I interferons.

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Conflict of interest statement

Disclosure statement Supported by the National Research Science Award T32 program (grant 232A1007512-38 [to M.T.L.]), the Brigham and Women’s Department of Medicine and the Rheumatology Fellowship Training Program (to C.A.R.), the Samara Jan Turkel Clinical Center for Pediatric Autoimmune Disease (to M.B.S.), the Rheumatology Research Foundation R Bridge Award and Innovative Research Award (to P.Y.L.), and the Boston Children’s Hospital Translational Research Program Pilot Award (to P.Y.L.). Disclosure of potential conflict of interest: The authors declare that they have no relevant conflicts of interest.

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