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. 1985 Dec;60(12):1180-2.
doi: 10.1136/adc.60.12.1180.

Premature thelarche: a follow up study of 40 girls. Natural history and endocrine findings

A M Pasquino, L Tebaldi, L Cioschi, C Cives, G Finocchi, M Maciocci, G Mancuso, B Boscherini

Premature thelarche: a follow up study of 40 girls. Natural history and endocrine findings

A M Pasquino et al. Arch Dis Child. 1985 Dec.

Abstract

Follow up of 40 girls with premature thelarche showed that where this disorder occurred before age 2 years it usually regressed completely, thus representing a transient and isolated phenomenon. Premature thelarche after age 2 years persisted more frequently, however, and represented the first sign of sexual development, generally leading to simple early puberty.

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