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. 1985 Dec;20(6):703-6.
doi: 10.1111/j.1365-2125.1985.tb05134.x.

Antipyrine clearance and metabolite formation in children with congenital adrenal hyperplasia

M W Teunissen, G J Bruining, B M De Jongh, E W Tenkate-Westerhof, D D Breimer

Antipyrine clearance and metabolite formation in children with congenital adrenal hyperplasia

M W Teunissen et al. Br J Clin Pharmacol. 1985 Dec.

Abstract

Antipyrine salivary clearance and half-life and the rate of formation of three principal metabolites of antipyrine (4-hydroxyantipyrine, 3-hydroxymethylantipyrine and norantipyrine) were assessed in nine children with congenital adrenal hyperplasia, six of whom were salt-losers and three of whom were non-salt-losers. No differences were found in comparison with data obtained in normal children.

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