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. 2025 Oct 8;30(31):105328.
doi: 10.1016/j.jaccas.2025.105328. Epub 2025 Sep 8.

Persistent Fifth Aortic Arch in a Right-Sided Aortic Arch Associated With Tetralogy of Fallot

Gajon Uthayakumaran  1 , Matthew Liava'a  1 , Julian Ayer  2 , David Murphy  1 , Claire Lawley  3
Affiliations

Persistent Fifth Aortic Arch in a Right-Sided Aortic Arch Associated With Tetralogy of Fallot

Gajon Uthayakumaran et al. JACC Case Rep. .

Abstract

Persistent fifth aortic arch is a rare congenital cardiac anomaly. We report the imaging findings of a subtype of persistent fifth aortic arch in an infant with tetralogy of Fallot and a right-sided aortic arch.

Keywords: aorta; hybrid imaging; tetralogy of Fallot.

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Conflict of interest statement

Funding Support and Author Disclosures The authors have reported that they have no relationships relevant to the contents of this paper to disclose.

Figures

None
Graphical abstract
Figure 1
Figure 1
Cross Sectional Imaging Demonstrating a Persistent Fifth Aortic Arch in a Right-Sided Aortic Arch Associated With Tetralogy of Fallot, and Comparison With Aortic arch Embryology (A) Subcostal oblique 2D echocardiogram image demonstrating a large perimembranous ventricular septal defect (∗) with anterocephalad deviation of the outlet septum (#) consistent with tetralogy of Fallot. (B) Suprasternal 2D and color echocardiogram image demonstrating a right-sided aortic arch with a dual lumen. (C and D) Sagittal and coronal computed tomography images demonstrating a right aortic arch with a dual lumen. Each lumen is marked with an asterisk (∗). (E) 3D reconstruction demonstrating a persistent fifth aortic arch. (F) Normal aortic arch embryology.
See this image and copyright information in PMC

References

    1. Shan H., Du X., Zheng G., Ke T., Liao C., Yang H. Persistent fifth aortic arch: a comprehensive literature review. Front Pediatr. 2023;11 - PMC - PubMed
    1. Oppido G., Davies B. Subclavian artery from ascending aorta or as the first branch of the aortic arch: another variant of persistent fifth aortic arch. J Thorac Cardiovasc Surg. 2006;132(3):730–731. - PubMed

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