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Editorial
. 2025 Oct;211(10):1740-1742.
doi: 10.1164/rccm.202508-2007ED.

Who Will Evolve from Interstitial Lung Abnormalities to Interstitial Lung Disease? Early Radio-Proteomic Warning Signals in the Lung

David J Nagel  1 , Eleanor Valenzi  2
Affiliations
Editorial

Who Will Evolve from Interstitial Lung Abnormalities to Interstitial Lung Disease? Early Radio-Proteomic Warning Signals in the Lung

David J Nagel et al. Am J Respir Crit Care Med. 2025 Oct.
No abstract available

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Figures

Figure 1.
Figure 1.
Summary of study design, cohorts included, key results, and suggested future directions for this evaluation of HAA radio-proteomic biomarkers and the aggregate field of biomarkers for ILD. CT = computed tomography; HAA = high attenuation area; ILA = interstitial lung abnormality; ILD = interstitial lung disease; MAPK = mitogen-activated protein kinase.
See this image and copyright information in PMC

Comment on

  • Associations of High Attenuation Area-Related Proteomic Biomarkers with Fibrotic or Subpleural Interstitial Lung Abnormalities.
    Kim JS, Debban CL, Guzman DE, Hannan RT, Salvatore M, McGroder C, Zhang D, Podolanczuk AJ, Duprez DA, Ma SF, Huang Y, Sturek JM, Rich SS, Rotter JI, Deo R, Dubin RF, Pugashetti JV, Wang JM, Han MK, Oldham JM, Noth I, Woodruff PG, Ortega VE, Fanburg-Smith JC, Stelow EB, Moskaluk CA, Hoffman EA, Garcia CK, Bowler RP, Ganz P, Barr RG, Manichaikul A. Kim JS, et al. Am J Respir Crit Care Med. 2025 Oct;211(10):1811-1822. doi: 10.1164/rccm.202503-0610OC. Am J Respir Crit Care Med. 2025. PMID: 40845333 Free PMC article.

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    1. Kim JS, Debban CL, Guzman D, Hannan RT, Salvatore M, McGroder C. et al. Associations of high attenuation area-related proteomic biomarkers with fibrotic or subpleural interstitial lung abnormalities. Am J Respir Crit Care Med . 2025;211:1811–1822. - PMC - PubMed

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