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Review
. 2026 Jan 15:579:120581.
doi: 10.1016/j.cca.2025.120581. Epub 2025 Sep 7.

Lipoprotein(a) in neoplastic transformation

Dan-Qi Han  1 , Tian-Yi Ma  1 , Duo-Hong Wu  2 , Shi-Juan Lu  3 , Jiang-Hua Zhong  4 , Jian-Jun Li  5
Affiliations
Review

Lipoprotein(a) in neoplastic transformation

Dan-Qi Han et al. Clin Chim Acta. .

Abstract

Cardiovascular diseases and cancer are top global causes of death, sharing risk factors and treatment strategies. Although dyslipidemia is linked to both, its exact roles are unclear. Recent studies suggest a potential association between plasma lipoprotein(a) levels and cancer risk. This review compiles the latest on lipoprotein(a)'s relation to several cancers and explores potential underlying mechanisms, aiming to deepen understanding of its role in cancer.

Keywords: CVD; Cancer; Clinical evidence; Lipoprotein(a).

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Conflict of interest statement

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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