Crohn's disease exclusion diet as an add-on to antitumor necrosis factor-α therapy in children with moderate-to-severe Crohn's disease

Collaborators, Affiliations

Meyer Children's Hospital IRCCS Gastroenterology and Nutrition Research Group:
Elena Banci⁴, Alessia De Blasi¹, Martina Di Benedetto¹, Irene Dalpiaz¹

¹ Gastroenterology and Nutrition Unit, Meyer Children's Hospital IRCCS, Florence, Italy.
² Department NEUROFARBA, University of Florence, Florence, Italy.
³ Division of Pediatrics, Department of Health Sciences, University of Piemonte Orientale, Novara, Italy.
⁴ Dietetics Unit, Meyer Children's Hospital IRCCS, Florence, Italy.

Saverio Pochesci et al. J Pediatr Gastroenterol Nutr. 2025 Nov.

. 2025 Nov;81(5):1237-1241.

doi: 10.1002/jpn3.70208. Epub 2025 Sep 10.

Meyer Children's Hospital IRCCS Gastroenterology and Nutrition Research Group:
Elena Banci⁴, Alessia De Blasi¹, Martina Di Benedetto¹, Irene Dalpiaz¹

¹ Gastroenterology and Nutrition Unit, Meyer Children's Hospital IRCCS, Florence, Italy.
² Department NEUROFARBA, University of Florence, Florence, Italy.
³ Division of Pediatrics, Department of Health Sciences, University of Piemonte Orientale, Novara, Italy.
⁴ Dietetics Unit, Meyer Children's Hospital IRCCS, Florence, Italy.

No abstract available

Keywords: biological therapies; inflammatory bowel diseases; whole‐food nutritional therapy.

References

1. Hanauer SB, Feagan BG, Lichtenstein GR, et al. Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial. Lancet. 2002;359(9317):1541‐1549.
1. Hyams JS, Griffiths A, Markowitz J, et al. Safety and efficacy of adalimumab for moderate to severe Crohn's disease in children. Gastroenterology. 2012;143(2):365‐374.e2.
1. van Rheenen PF, Aloi M, Assa A, et al. The medical management of paediatric Crohn's disease: an ECCO‐ESPGHAN guideline update. J Crohns Colitis. 2020;15:jjaa161.
1. Levine A, Wine E, Assa A, et al. Crohn's disease exclusion diet plus partial enteral nutrition induces sustained remission in a randomized controlled trial. Gastroenterology. 2019;157(2):440‐450.e8.
1. Scarallo L, Banci E, Pierattini V, Lionetti P. Crohn's disease exclusion diet in children with Crohn's disease: a case series. Curr Med Res Opin. 2021;37(7):1115‐1120.