Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2025 Sep 11.
doi: 10.1007/s00467-025-06958-0. Online ahead of print.

A new era of complement inhibition: are we ready for the infectious risks?

Affiliations
Editorial

A new era of complement inhibition: are we ready for the infectious risks?

Nicolas Bergeron et al. Pediatr Nephrol. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

Declarations. Conflict of interest: The authors have no competing interests to declare that are relevant to the content of this article.

References

    1. Konar M, Granoff DM (2017) Eculizumab treatment and impaired opsonophagocytic killing of meningococci by whole blood from immunized adults. Blood 130:891–899 - DOI - PubMed - PMC
    1. Socié G, Caby-Tosi MP, Marantz JL, Cole A, Bedrosian CL, Gasteyger C, Mujeebuddin A, Hillmen P, Vande Walle J, Haller H (2019) Eculizumab in paroxysmal nocturnal haemoglobinuria and atypical haemolytic uraemic syndrome: 10-year pharmacovigilance analysis. Br J Haematol 185:297–310 - DOI - PubMed - PMC
    1. McNamara LA, Topaz N, Wang X, Hariri S, Fox L, MacNeil JR (2017) High risk for invasive meningococcal disease among patients receiving Eculizumab (Soliris) despite receipt of meningococcal vaccine. MMWR Morb Mortal Wkly Rep 66:734–737 - DOI - PubMed - PMC
    1. Starck L, Nummi V, Poikonen E, Lehtinen AE, Kivelä P, Friberg N, Torvikoski J, Toropainen M, Meri S (2025) Meningococcal sepsis in patient with paroxysmal nocturnal hemoglobinuria during pegcetacoplan therapy. Emerg Infect Dis 31:583–586 - DOI - PubMed - PMC
    1. Perkovic V, Barratt J, Rovin B, Kashihara N, Maes B, Zhang H, Trimarchi H, Kollins D, Papachristofi O, Jacinto-Sanders S, Merkel T, Guerard N, Renfurm R, Hach T, Rizk DV, APPLAUSE-IgAN Investigators (2025) Alternative complement pathway inhibition with Iptacopan in IgA nephropathy. N Engl J Med 392:531–543 - DOI - PubMed

Publication types

LinkOut - more resources