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. 2025 Sep 1;73(5):1004-1011.
doi: 10.4103/neurol-india.Neurol-India-D-23-00499. Epub 2025 Sep 13.

Study of Concordance and Discordance between Preoperative Magnetic Resonance Imaging Findings and Intraoperative Findings in Peripheral Nerve Pathologies

Rohan R Roy  1 , Alay V Khandhar  1 , Aditi D Erande  2 , Smriti J Mulani  3 , Ketan I Desai  1
Affiliations
Free article

Study of Concordance and Discordance between Preoperative Magnetic Resonance Imaging Findings and Intraoperative Findings in Peripheral Nerve Pathologies

Rohan R Roy et al. Neurol India. .
Free article

Abstract

Background: It is important that the peripheral nerve (PN) pathologies are identified early as most patients are young, and delay in treatment can have lasting implications. Magnetic resonance imaging (MRI) is routinely used in formulating an appropriate management plan.

Objectives: This study was aimed at assessing usefulness and efficacy of MRI in diagnosing PN pathologies by comparing the preoperative MRI findings with the intraoperative findings, thereby helping in prognostication and treatment planning.

Methods and material: It was a double-blind prospective, nonrandomized study of diagnostic efficacy that was conducted on 95 surgically treated patients with PN pathologies in the Department of Neurosurgery. The radiologist conducted a preoperative MRI evaluation, while one of the coauthors from the operating team had no access to the preoperative MRI scan findings. The senior operating neurosurgeon evaluated intraoperative findings, keeping the radiologist blind. The data were then compared to determine concordance and discordance between the two findings. Cohen's Kappa test was used for agreement. Diagnostic analysis was performed using Medcalc software (version 22). A P value less than 0.05 was considered significant.

Results: We found that the overall sensitivity of MRI for diagnosing PN problems was 97.52%, with a specificity of 91.95%, a positive predictive value of 89.39%, and a negative predictive value of 98.16%. The overall accuracy was found to be 94.24%, with Cohen's kappa value of 0.88, showing a strong level of agreement.

Conclusions: MRI is an effective tool that helps in accurately diagnosing a plethora of PN problems with significant intraoperative correlation, ultimately helping in patient care and management.

Keywords: Diagnostic efficacy; magnetic resonance imaging; peripheral nerve pathology.

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