Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Sep 15.
doi: 10.1007/s11673-025-10437-4. Online ahead of print.

Should We Just Prescribe? Ethical Considerations When Using Antidepressants and Benzodiazepines For Emotional Distress

Affiliations

Should We Just Prescribe? Ethical Considerations When Using Antidepressants and Benzodiazepines For Emotional Distress

G García-Calderó et al. J Bioeth Inq. .

Abstract

Prescribing antidepressants and benzodiazepines for patients with emotional distress is a common practice in primary healthcare that raises certain ethical questions. This paper has three aims. First, to describe the motivations that lead general practitioners to prescribe antidepressants and benzodiazepines in these cases. Second, to reflect on the ethical implications of such prescriptions based on the four principles of biomedical ethics defined by Beauchamp and Childress (autonomy, nonmaleficence, beneficence, and justice). Finally, to propose some recommendations for the mitigation of the medicalization of emotional distress in primary healthcare. Results show that general practitioners seek to alleviate patients' suffering but their prescribing decisions are influenced by some uncertainties in clinical judgement as well as by systemic factors (patients' pressures, time constraints, and unawareness of resources). Ethical issues arise in relation to the potential for dependence, the questionable long-term benefit of prescriptions, the uncritical fulfillment of patients' expectations, and the impediment to address underlying social issues or to develop patients' capabilities. Clinical consultation should be founded on effective communication between doctors and patients and a holistic care approach that acknowledges the psychological, social, and existential dimensions should replace a merely symptomatic approach. Some strategies to mitigate medicalization are proposed: the promotion of regular monitoring visits with patients and multidisciplinary collaboration, the enhancement of physicians' knowledge about non-pharmacological interventions, as well as the establishment of an evidence-base for the effectiveness of these drugs in the primary healthcare setting.

Keywords: Antidepressants; Benzodiazepines; Bioethics; Emotional distress; Medicalization; Primary Healthcare.

PubMed Disclaimer

Conflict of interest statement

Declarations. Ethical Approval: Not applicable, no primary data has been collected. Competing interests: Authors declare no conflicts of interests.

References

    1. Anthierens, S., H. Habraken, M. Petrovic, and T. Christiaens. 2007. The lesser evil? Initiating a benzodiazepine prescription in general practice: A qualitative study on GPs’ perspectives. Scandinavian Journal of Primary Health Care 25(4): 214–219. - DOI - PubMed - PMC
    1. Archer, C., N. Wiles, D. Kessler, C.A. Chew-Graham, and K. Turner. 2024. Prescribing benzodiazepines in young adults with anxiety: A qualitative study of GP perspectives. British Journal of General Practice 74(748): e742–e748. - DOI
    1. Beauchamp, T. L., and J.F. Childress. 1994. Principles of biomedical ethics. Oxford University Press.
    1. Binder, P.-E. 2022. Suffering a healthy life—On the existential dimension of health. Frontiers in Psychology 13. https://doi.org/10.3389/fpsyg.2022.803792
    1. Callahan, D. 1996. The goals of medicine: Setting new priorities. Hastings Center Report 26(6): 1–54. - DOI

LinkOut - more resources