Emapalumab for Maladaptive Interferon-γ-Mediated Inflammation in Drug Reaction With Eosinophilia and Systemic Symptoms Complicating First-Line Antituberculosis Therapy

Affiliations

¹ Division of Bone Marrow Transplantation and Immune Deficiency, Cancer and Blood Diseases Institute, Cincinnati Children's Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
² Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.

Yahya Almodallal et al. Pediatr Blood Cancer. 2025 Dec.

. 2025 Dec;72(12):e32052.

doi: 10.1002/pbc.32052. Epub 2025 Sep 16.

¹ Division of Bone Marrow Transplantation and Immune Deficiency, Cancer and Blood Diseases Institute, Cincinnati Children's Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
² Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.

No abstract available

References

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1. C. Bracaglia, D. P. Marafon, I. Caiello, et al., “High Levels of Interferon‐Gamma (IFNγ) in Macrophage Activation Syndrome (MAS) and CXCL9 Levels as a Biomarker for IFNγ Production in MAS,” Pediatric Rheumatology 13 (2015): 1–2.
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