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. 2025 Aug;10(1):297-311.
doi: 10.1016/j.yaoo.2025.02.010. Epub 2025 Jun 27.

Ocular Manifestations of Giant Cell Arteritis

Timothy Do  1 , Gaurav Gulati  2 , Han S Lee  3 , Branden Cord  4 , Maryam Ghiassi  5 , Lotfi Hacein-Bey  6 , Yin Allison Liu  7
Affiliations

Ocular Manifestations of Giant Cell Arteritis

Timothy Do et al. Adv Ophthalmol Optom. 2025 Aug.
No abstract available

Keywords: Giant cell arteritis; irreversible blindness; ischemic vasculitis; ocular imaging modalities; ocular manifestation.

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Conflict of interest statement

Disclosure Statement: The Authors have nothing to disclose

Figures

Figure 1:
Figure 1:
Blood supply to the retina. From Stroke.2021;52:e282-e294 ©2021 American Heart Association, Inc., with permission.
Figure 2:
Figure 2:
[A] is a normal OPTOS widefield image of the right eye which is the unaffected eye. [B] is an OPTOS widefield image of the left eye, which was affected with a cilioretinal artery occlusion. The cotton wool spot (yellow arrow) can be appreciated along the inferior aspect of the macula. [C] is an optical coherence tomography of the left eye affected with the cilioretinal artery occlusion and a paracentral acute middle maculopathy (red arrow) can be appreciated by the hyperreflective (whitening) band-like lesion in the inner nuclear layer of the retina along the inferior aspect of the macula. [D] is a fluorescein angiogram of the left eye affected with the cilioretinal artery occlusion demonstrating delayed filling (green arrow) in the inferior aspect of the macula.
Figure 3:
Figure 3:
CDUS of a TAB specimen demonstrating classical hypoechoic halo sign of GCA (arrows). (Left) Cross sectional view. (Right) Longitudinal view. From “The impact of temporal artery biopsy on surgical practice” by A. Cristaudo 2016 with permission.
See this image and copyright information in PMC

References

    1. Li KJ, Semenov D, Turk M, Pope J. A meta-analysis of the epidemiology of giant cell arteritis across time and space. Arthritis Res Ther. Mar 11 2021;23(1):82. doi: 10.1186/s13075-021-02450-w - DOI - PMC - PubMed
    1. El-Dairi MA, Chang L, Proia AD, Cummings TJ, Stinnett SS, Bhatti MT. Diagnostic Algorithm for Patients With Suspected Giant Cell Arteritis. Journal of Neuro-Ophthalmology. 2015;35(3):246–253. doi: 10.1097/wno.0000000000000234 - DOI - PubMed
    1. Ponte C, Grayson PC, Robson JC, et al. 2022 American College of Rheumatology/EULAR classification criteria for giant cell arteritis. Annals of the Rheumatic Diseases. 2022;81(12):1647–1653. doi: 10.1136/ard-2022-223480 - DOI - PubMed
    1. Bilton EJ, Mollan SP. Giant cell arteritis: reviewing the advancing diagnostics and management. Eye. 2023/08/01 2023;37(12):2365–2373. doi: 10.1038/s41433-023-02433-y - DOI - PMC - PubMed
    1. Ponte C, Rodrigues AF, O’Neill L, Luqmani RA. Giant cell arteritis: Current treatment and management. World J Clin Cases. Jun 16 2015;3(6):484–94. doi: 10.12998/wjcc.v3.i6.484 - DOI - PMC - PubMed

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