Clesrovimab in Infants and Children at Increased Risk for Severe RSV Disease

Heather J Zar¹, Louis J Bont², Paolo Manzoni³, Flor M Muñoz⁴, Octavio Ramilo⁵, Po-Yen Chen⁶, José M Novoa⁷, Gustavo A Ordoñez⁸, Maria Tsolia⁹, Bruce Tapiéro¹⁰, Mirta I Acuña-Ávila¹¹, Javier M Castellanos¹², Michael Meyer¹³, Ichiro Morioka¹⁴, Ziqiang Chen¹⁵, Radha A Railkar¹⁵, Xiaowei Zang¹⁵, Brian M Maas¹⁵, Andrea Likos¹⁵, Andrew W Lee¹⁵, Luis A Castagnini¹⁵, Anushua Sinha¹⁵; SMART (MK-1654-007) Study Group

Collaborators, Affiliations

Collaborators

SMART (MK-1654-007) Study Group:
Peter Richmond, Pita Birch, Bruce Tapiero, Ian Mitchell, Jose Manuel Novoa Pizarro, Mirta Isabel Acuna, Andres Maturana, Monica D'Amato, Gustavo Ordonez, William Ricardo Bachiller, Maristella Ayala, Zbynek Stranak, Hana Wiedermannova, Santtu Heinonen, Elodie Lecorps, Mandavi Rajguru, Olivier Tandonnet, Ulrich Thome, Mario Ruediger, Martin Wetzke, Brigitte Stiller, Emmanuel Roilides, Athanasios Michos, Maria Tsolia, Vassiliki Papaevangelou, Ellis Kam Lun Hon, Oi Yin Wong, Ferenc Dicso, Tamas Kovacs, Gyula Talosi, Csaba Nador, Laszlo Ablonczy, Gabor Boross, Eva Karoly, Ildiko Szucs, Renato Cutrera, Eugenio Baraldi, Andrea Ronchi, Susanna Maria Roberta Esposito, Zempei Kano, Ichiro Morioka, Junko Yamamoto, Tetsuya Isayama, Tetsuya Fukuoka, Hiroshi Kanda, Daigo Kajikawa, Chae Hee Chieng, Mariana Binti Daud, Kwi Sing Kwi Seah, Mia Tuang Koh, Asiah Kassim, Mehala Devi Baskaran, Efrain Montano Gonzalez, Daisy Jimenez, Miguel Angel Rodriguez Weber, Selene Najera, Javier Moises Castellanos Martinez, Michael Meyer, Haavard Ove Skjerven, Ildauro Aguirre Sosa, Tommy Leonel Prado Gomez, Zoe M Rodriguez, Kee Thai Yeo, Anthonet Lombard Koen, Shaun Lawrence Barnabas, Moherndran Archary, Buhle Nxumalo-Toba, Azeem Hassan Walele, Heather Joy Zar, Susana Ares Segura, Daniel Blazquez Gamero, Claudia Fortuny Guasch, Manuel Ramon Baca Cots, Josep-Lluis Arimany Montana, Gemma Ginovart Galiana, Fernando Cabanas Gonzalez, Belen Fenandez Colomer, Li-Min Huang, Cheng-Hsun Chiu, Hsin Chi, Po-Yen Chen, Kamolwish Laoprasopwattana, Thanyawee Puthanakit, Supattra Rungmaitree, Betul Ulukol, Benhur Sirvan Cetin, Derya Alabaz, Eray Esra Onal, Fuat Emre Canpolat, Mark Johnson, Eleri Adams, Jonathan M Cohen, Paul McNamara, Eva Princess Galiza, John T F Ho, Scott Robert Dobson, Jennifer Lynn Nayak, Michael Odom, Dinesh Kumar Pillai, Chi Hornik, Carlos Sabogal, Jaime Eduardo Fergie, Dynio Honrubia, Lisa Mcgill-Vargas, Zachary Willis, Pratik Parikh, Claudia M Espinosa, Austin Wei-Hong Chan, Tarak J Patel

Affiliations

¹ University of Cape Town, Cape Town, South Africa.
² UMC Utrecht, Utrecht, the Netherlands.
³ University of Torino Hospital Degli Infermi, Ponderano, Italy.
⁴ Baylor College of Medicine, Houston.
⁵ St. Jude Children's Research Hospital, Memphis, TN.
⁶ Taichung Veterans General Hospital, Taichung, Taiwan.
⁷ Hospital Padre Alberto Hurtado, Santiago, Chile.
⁸ Clínica Imbanaco, Cali, Colombia.
⁹ National and Kapodistrian University of Athens, Athens.
¹⁰ Centre Hospitalier Universitaire Sainte-Justine, Montreal.
¹¹ University of Chile, Santiago, Chile.
¹² Morales Vargas Centro de Investigación, León, Mexico.
¹³ Middlemore Hospital, Auckland, New Zealand.
¹⁴ Nihon University Itabashi Hospital, Tokyo.
¹⁵ Merck, Rahway, NJ.

PMID: 40961423
DOI: 10.1056/NEJMc2506107

Clesrovimab in Infants and Children at Increased Risk for Severe RSV Disease

Heather J Zar et al. N Engl J Med. 2025.

. 2025 Oct 2;393(13):1343-1345.

doi: 10.1056/NEJMc2506107. Epub 2025 Sep 17.

Authors

Collaborators

SMART (MK-1654-007) Study Group:
Peter Richmond, Pita Birch, Bruce Tapiero, Ian Mitchell, Jose Manuel Novoa Pizarro, Mirta Isabel Acuna, Andres Maturana, Monica D'Amato, Gustavo Ordonez, William Ricardo Bachiller, Maristella Ayala, Zbynek Stranak, Hana Wiedermannova, Santtu Heinonen, Elodie Lecorps, Mandavi Rajguru, Olivier Tandonnet, Ulrich Thome, Mario Ruediger, Martin Wetzke, Brigitte Stiller, Emmanuel Roilides, Athanasios Michos, Maria Tsolia, Vassiliki Papaevangelou, Ellis Kam Lun Hon, Oi Yin Wong, Ferenc Dicso, Tamas Kovacs, Gyula Talosi, Csaba Nador, Laszlo Ablonczy, Gabor Boross, Eva Karoly, Ildiko Szucs, Renato Cutrera, Eugenio Baraldi, Andrea Ronchi, Susanna Maria Roberta Esposito, Zempei Kano, Ichiro Morioka, Junko Yamamoto, Tetsuya Isayama, Tetsuya Fukuoka, Hiroshi Kanda, Daigo Kajikawa, Chae Hee Chieng, Mariana Binti Daud, Kwi Sing Kwi Seah, Mia Tuang Koh, Asiah Kassim, Mehala Devi Baskaran, Efrain Montano Gonzalez, Daisy Jimenez, Miguel Angel Rodriguez Weber, Selene Najera, Javier Moises Castellanos Martinez, Michael Meyer, Haavard Ove Skjerven, Ildauro Aguirre Sosa, Tommy Leonel Prado Gomez, Zoe M Rodriguez, Kee Thai Yeo, Anthonet Lombard Koen, Shaun Lawrence Barnabas, Moherndran Archary, Buhle Nxumalo-Toba, Azeem Hassan Walele, Heather Joy Zar, Susana Ares Segura, Daniel Blazquez Gamero, Claudia Fortuny Guasch, Manuel Ramon Baca Cots, Josep-Lluis Arimany Montana, Gemma Ginovart Galiana, Fernando Cabanas Gonzalez, Belen Fenandez Colomer, Li-Min Huang, Cheng-Hsun Chiu, Hsin Chi, Po-Yen Chen, Kamolwish Laoprasopwattana, Thanyawee Puthanakit, Supattra Rungmaitree, Betul Ulukol, Benhur Sirvan Cetin, Derya Alabaz, Eray Esra Onal, Fuat Emre Canpolat, Mark Johnson, Eleri Adams, Jonathan M Cohen, Paul McNamara, Eva Princess Galiza, John T F Ho, Scott Robert Dobson, Jennifer Lynn Nayak, Michael Odom, Dinesh Kumar Pillai, Chi Hornik, Carlos Sabogal, Jaime Eduardo Fergie, Dynio Honrubia, Lisa Mcgill-Vargas, Zachary Willis, Pratik Parikh, Claudia M Espinosa, Austin Wei-Hong Chan, Tarak J Patel

Affiliations

¹ University of Cape Town, Cape Town, South Africa.
² UMC Utrecht, Utrecht, the Netherlands.
³ University of Torino Hospital Degli Infermi, Ponderano, Italy.
⁴ Baylor College of Medicine, Houston.
⁵ St. Jude Children's Research Hospital, Memphis, TN.
⁶ Taichung Veterans General Hospital, Taichung, Taiwan.
⁷ Hospital Padre Alberto Hurtado, Santiago, Chile.
⁸ Clínica Imbanaco, Cali, Colombia.
⁹ National and Kapodistrian University of Athens, Athens.
¹⁰ Centre Hospitalier Universitaire Sainte-Justine, Montreal.
¹¹ University of Chile, Santiago, Chile.
¹² Morales Vargas Centro de Investigación, León, Mexico.
¹³ Middlemore Hospital, Auckland, New Zealand.
¹⁴ Nihon University Itabashi Hospital, Tokyo.
¹⁵ Merck, Rahway, NJ.

PMID: 40961423
DOI: 10.1056/NEJMc2506107

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Clesrovimab in Infants and Children at Increased Risk for Severe RSV Disease

Collaborators

Affiliations

Clesrovimab in Infants and Children at Increased Risk for Severe RSV Disease

Authors

Collaborators

Affiliations

Publication types

LinkOut - more resources

Full Text Sources