Intestinal capillary blood flow studied with fluorescein flowmetry in hemorrhagically shocked rats
- PMID: 4096170
Intestinal capillary blood flow studied with fluorescein flowmetry in hemorrhagically shocked rats
Abstract
The intestinal capillary blood flow in hemorrhagic shock was studied in 32 rats by fluorescein flowmetry (FF). FF implies the measurement of relative intestinal capillary blood flow, expressed as an index. Exsanguination to 35 mmHg for 180 min resulted in a heterogeneous fluorescence pattern with 51% difference in blood flow index between the areas with most and those with least fluorescence, compared with 14% in the control group. Following retransfusion of the shed blood, the difference in blood flow index between areas with most and least fluorescence was 54%, suggesting that the heterogeneous blood flow was not improved by retransfusion. Heterogeneity of the capillary blood flow in the intestines seems to be a phenomenon of hemorrhagic shock and FF to be a suitable method for studying this condition.
Similar articles
-
Fluorescein flowmetry: a method for measuring relative capillary blood flow in the intestine.Clin Physiol. 1985 Jun;5(3):281-92. Clin Physiol. 1985. PMID: 4006409
-
Mechanisms involved in the effect of M6434 on experimental hemorrhagic shock: II. Effects on energy metabolism and organ blood flow.Circ Shock. 1989 Mar;27(3):183-91. Circ Shock. 1989. PMID: 2706753
-
[Microcirculation of the liver in hemorrhagic shock in the rat and its significance for energy metabolism and function].Zentralbl Chir. 1993;118(4):218-25. Zentralbl Chir. 1993. PMID: 8493831 German.
-
[Studies on the prediction of intestinal recovery from ischemic injury by fluorescein fluorescence patterns].Nihon Geka Gakkai Zasshi. 1984 Jan;85(1):56-64. Nihon Geka Gakkai Zasshi. 1984. PMID: 6738489 Japanese.
-
Capillary filtration coefficient: the technique and its application to the small intestine.Cardiovasc Res. 1979 Oct;13(10):547-61. doi: 10.1093/cvr/13.10.547. Cardiovasc Res. 1979. PMID: 42491 Review.