Fluid Therapy in the Hypoalbuminemic Patient

Abstract

Albumin has several key roles in the body, and hypoalbuminemia interferes with homeostasis in many organs. This article reviews the synthesis and structure of albumin, metabolism, primary functions, and causes and complications of hypoalbuminemia. Diagnostic and therapeutic strategies in patients with hypoalbuminemia should focus on identifying and treating the underlying cause while supporting normal tissue perfusion. Fluid therapy for patients with clinical manifestations of low-serum albumin requires an understanding of the risks and benefits of crystalloids and colloid solutions available.

Keywords: Colloid osmotic pressure; Edema; Fluid therapy; Hypoalbuminemia; Oncotic pressure.