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. 2025 Sep 18.
doi: 10.1007/s12013-025-01891-3. Online ahead of print.

Molecular Simulation and Expression Analysis of Vitamin C and Curcumin in Mitigating Buprofezin-induced Genotoxicity and Inflammatory Responses in Balb/c Mice

Haleema Sadia  1 , Irfan Zia Qureshi  2 , Muhammad Naveed  3 , Tariq Aziz  4 , Manal F Elkhadragy  5 , Maher S Alwethaynani  6 , Fahad Al-Asmari  7 , Areej A Alhhazmi  8 , Hanan Abdulrahman Sagini  9 , Suad Hamdan Almasoudi  10 , Fakhria A Al-Joufi  11
Affiliations

Molecular Simulation and Expression Analysis of Vitamin C and Curcumin in Mitigating Buprofezin-induced Genotoxicity and Inflammatory Responses in Balb/c Mice

Haleema Sadia et al. Cell Biochem Biophys. .
No abstract available

Keywords: Buprofezin; Curcumin; Genotoxicity; Inflammation; Vitamin c.

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Conflict of interest statement

Declarations. Conflict of Interest: The authors declare no competing interests. Arrive Statement: This study was conducted in strict accordance with the “European Union Guidelines on Animals” and the “UK Animals Scientific Procedures Act (1986),” which provide comprehensive regulations on the use of animals in scientific research. Additionally, the study complied with the “European Communities Council Directive” (86/609/EEC), issued on November 24, 1986, and adhered to the ethical principles outlined in the Declaration of Helsinki. Ethical approval for the study was granted by the Bioethical Committee at the Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, under clearance No. BEC-FBS-QAU-2022-407.

References

    1. Alengebawy, A., Abdelkhalek, S. T., Qureshi, S. R., & Wang, M. Q. (2021). Heavy metals and pesticides toxicity in agricultural soil and plants: Ecological risks and human health implications. Toxics, 9(3), 42. https://doi.org/10.3390/toxics9030042 - DOI - PubMed - PMC
    1. Ji, X., Xue, Y., Zhang, H., Jiang, W., Xu, X., & Chen, W. (2016). Metabolic responses in common carp (Cyprinus Carpio L.) exposed to buprofezin: The oxidative stress effects of buprofezin on carp liver. Aquatic Toxicology, 178, 86–94. https://doi.org/10.1016/j.aquatox.2016.07.015 - DOI
    1. Qureshi, S. R., Bibi, A., & Rehan, M. (2016). Oxidative stress and biochemical disruption in common carp (Cyprinus carpio) exposed to buprofezin. Fish Physiology and Biochemistry, 42(3), 647–656. https://doi.org/10.1007/s10695-015-0168-4 - DOI
    1. Ren, Z., Wu, X., & Lu, Y. (2022). Buprofezin induces oxidative stress and damages the energy metabolism system in liver of rats. Toxicology Letters, 352, 43–50. https://doi.org/10.1016/j.toxlet.2021.12.014 - DOI
    1. De Cock, A., & Degheele, D. (1998). Effects of buprofezin on the development of whitefly eggs and nymphs (Homoptera: Aleyrodidae). Journal of Economic Entomology, 91(3), 573–579. https://doi.org/10.1093/jee/91.3.573 - DOI

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