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Review
. 2025 Sep 19;15(1):32618.
doi: 10.1038/s41598-025-09349-5.

(Cardiac) complexity needs interaction

Tim De Coster  1   2
Affiliations
Review

(Cardiac) complexity needs interaction

Tim De Coster. Sci Rep. .

Abstract

The heart exemplifies a complex system where electrical, mechanical, and biochemical processes interact dynamically. Understanding cardiac complexity requires exploring these interactions across multiple levels, from cellular dynamics to organ-wide behavior. This collection examines key interactions in cardiology, including excitation-contraction coupling, arrhythmia quantification, electromechanical modeling, and imaging advances. By integrating mathematical, computational, and clinical perspectives, researchers uncover novel insights into heart function and dysfunction. Progress in this field relies on interdisciplinary collaboration, emphasizing the vital role of human interaction in translating discoveries into improved diagnostics and treatments.

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Figures

Fig. 1
Fig. 1
An overview of the complexity and interaction of different problems in cardiology, which can only be tackled using an equally complex interaction between scientific disciplines and expertise.
See this image and copyright information in PMC

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