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Case Reports
. 2025 Sep 4:16:1633982.
doi: 10.3389/fphar.2025.1633982. eCollection 2025.

Sulbactam-durlobactam combination therapy for carbapenem-resistant Acinetobacter baumannii sepsis with cutaneous involvement in an infant with acute monocytic leukemia: A case report

Chunxi Fu  1   2 , Xue Tang  1   2 , Xia Guo  1   2 , Liang Huang  2   3   4 , Ju Gao  1   2 , Rong Yang  1   2
Affiliations
Case Reports

Sulbactam-durlobactam combination therapy for carbapenem-resistant Acinetobacter baumannii sepsis with cutaneous involvement in an infant with acute monocytic leukemia: A case report

Chunxi Fu et al. Front Pharmacol. .

Abstract

Carbapenem-resistant Acinetobacter baumannii (CRAb) causes severe infections and poses significant treatment challenges. Sulbactam-durlobactam (SUL-DUR) is a novel antibiotic, but its use in children and infants has not been reported. We reported the first case of an infant with acute leukemia successfully treated with SUL-DUR for CRAb sepsis with cutaneous involvement.

Keywords: carbapenem-resistant Acinetobacter baumannii; case report; infant; sepsis; sulbactam-durlobactam.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

FIGURE 1
FIGURE 1
Time course of skin abscess (The day of the first occurrence of fever is regarded as the first day).
FIGURE 2
FIGURE 2
Timeline diagram of disease and treatment course. CRP, C-reactive protein; WBC, White Blood Cell; NEUT, Neutrophil; SUL-DUR, sulbactam-durlobactam; CEF-SUL, Cefoperazone-Sulbactam.
See this image and copyright information in PMC

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