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Review
. 2025 Dec;15(4):100901.
doi: 10.1016/j.afjem.2025.100901. Epub 2025 Sep 2.

Artificial intelligence in clinical toxicology in Africa: Emerging applications and barriers

Affiliations
Review

Artificial intelligence in clinical toxicology in Africa: Emerging applications and barriers

Mikiyas G Teferi et al. Afr J Emerg Med. 2025 Dec.

Abstract

Artificial intelligence (AI) has a supplementary role in clinical toxicology in Africa, addressing key challenges such as delayed diagnoses, limited expertise, and inadequate healthcare infrastructure. This method has the potential to increase diagnostic accuracy, optimize treatment strategies, and advance research on toxic substance exposure and poisoning cases. AI-driven tools, including machine learning algorithms and decision-support systems, enhance the early detection and risk assessment of toxicities. AI-powered predictive models facilitate precision medicine by designing treatment plans for individual patient profiles. Integrating this in telemedicine expands access to toxicology expertise, particularly in resource-limited settings. Additionally, AI accelerates research by analyzing large datasets, identifying trends, and predicting toxicological risks, thus contributing to public health interventions. Despite these advancements, challenges such as data poverty, ethical issues, and restrictive policies hinder its full potential in African healthcare. These gaps can be bridged through policy reforms, capacity-building initiatives, and robust AI frameworks, which will be crucial in maximizing AI benefits for clinical toxicology. This narrative review highlights the emerging applications of AI in Africa, emphasizing the need for collaborative efforts to ensure equitable and effective implementation. However, its adoption is limited by financial constraints, scarce datasets, weak infrastructure, and ethical concerns.

Keywords: Africa; Artificial intelligence; Clinical toxicology; Emergency medicine; Machine learning; Treatment.

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Conflict of interest statement

The author(s) declare no conflict of interest.

Figures

Fig 1:
Fig. 1
AI workflow in clinical toxicology figure created by the authors using Canva (www.canva.com).
Fig 2:
Fig. 2
AI-enabled public health interventions in toxicology (Figure created by the authors using Canva (www.canva.com).

References

    1. Bertrand P., Ahmed H., Ngwafor R., Frazzoli C. Toxicovigilance systems and practices in Africa. Toxics. 2016;4(3):13. - PMC - PubMed
    1. World Health Organization . World Health Organization; Geneva: 2014. Statistiques sanitaires mondiales 2012.http://www.who.int/healthinfo/global_burden_disease/estimates/en/index1.... [cited 2025 Apr 5]. Available from.
    1. World Health Organization. Leading causes of DALYs [Internet]. [cited 2025 Apr 5]. Available from: https://www.who.int/data/gho/data/themes/mortality-and-global-health-est....
    1. Chelkeba L., Mulatu A., Feyissa D., Bekele F., Tesfaye B.T. Patterns and epidemiology of acute poisoning in Ethiopia: a systematic review of observational studies. Arch Public Health. 2018;76:34. - PMC - PubMed
    1. World Health Organization. Snakebite envenoming [Internet]. [cited 2025 Apr 5]. Available from: https://www.who.int/teams/control-of-neglected-tropical-diseases/snakebi....

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