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. 2025 Jun 23;10(9):3271-3275.
doi: 10.1016/j.ekir.2025.06.039. eCollection 2025 Sep.

New Insights Into Renal Involvement During Immune-Mediated Thrombotic Thrombocytopenic Purpura

Marie Robert  1   2 , Valentin Maisons  3   4 , Marion Rabant  5   6 , Aude Servais  7 , Charles Antunes  8 , Nicolas Fage  9 , Florent von Tokarski  10 , Sophie Chauvet  11 , Manon Dekeyser  12 , Alain Wynckel  13 , Anna Duval  14 , Nadine Baroukh  3   15 , Agnès Veyradier  2   16   17 , Bérangère S Joly  2   16   17 , Paul Coppo  1   2   17 , Jean-Michel Halimi  3   15   18 ; MATRIX Consortium Group and the MATHIS Group
Collaborators, Affiliations

New Insights Into Renal Involvement During Immune-Mediated Thrombotic Thrombocytopenic Purpura

Marie Robert et al. Kidney Int Rep. .
No abstract available

Keywords: biopsy; immune-mediated thrombotic thrombocytopenic purpura; kidney; thrombotic microangiopathies.

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Figures

Figure 1
Figure 1
Representative images of 2 patients with immune-mediated thrombotic thrombocytopenic purpura. (1) Patient with renal TMA in the context of systemic sclerosis: (a) arteriolar thrombosis in the preglomerular arteriole (star), and double contours (arrow) (PAS staining, x40); (b) endothelial swelling (star) and double contours (arrow) (Jones staining, x40). (2) Patient with nonrenal TMA in the context of endocarditis: (c) (PAS staining x20) and (d) (Masson Trichrome staining x20) showing glomeruli with mesangial hypertrophy and hypercellularity, endocapillary hypercellularity with neutrophils, and cellular crescent with fibrinoid necrosis. PAS, periodic acid-schiff; TMA, thrombotic microangiopathy.
See this image and copyright information in PMC

References

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