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. 1970 Jul;25(4):423-6.
doi: 10.1136/thx.25.4.423.

Quantitative immunoelectrophoretic analysis in patients with tuberculosis and sarcoidosis

H G Clarke, T Freeman, R Hickman, W E Pryse-Phillips

Quantitative immunoelectrophoretic analysis in patients with tuberculosis and sarcoidosis

H G Clarke et al. Thorax. 1970 Jul.

Abstract

A study of 12 immunologically distinct serum proteins has been made in two conditions, tuberculosis and sarcoidosis, which have in common the formation of giant-cell granulomata. Significantly (p<0·001) higher concentrations of five proteins [α2 group component (GC), caeruloplasmin (caer), haptoglobin (hpt), haemopexin (hpx), and α1 easily precipitable glycoprotein (α1 PGp)] were found in tuberculosis. No significant differences from normal were found in patients with sarcoidosis. The results obtained compared to the available figures for conventional electrophoresis and the so-called `acute phase reaction' are discussed.

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