Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Sep 24:27:e81769.
doi: 10.2196/81769.

Critical Limitations in Systematic Reviews of Large Language Models in Health Care

Zvi Weizman  1
Affiliations

Critical Limitations in Systematic Reviews of Large Language Models in Health Care

Zvi Weizman. J Med Internet Res. .
No abstract available

Keywords: AI; LLM; artificial intelligence; clinical; digital health; health care; large language models; letter; review.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: None declared.

Comment on

References

    1. Li H, Fu JF, Python A. Implementing large language models in health care: clinician-focused review with interactive guideline. J Med Internet Res. 2025 Jul 11;27:e71916. doi: 10.2196/71916. doi. Medline. - DOI - PMC - PubMed
    1. Chang Y, Yin JM, Li JM, Liu C, Cao LY, Lin SY. Applications and future prospects of medical LLMs: a survey based on the M-KAT conceptual framework. J Med Syst. 2024 Dec 27;48(1):112. doi: 10.1007/s10916-024-02132-5. doi. Medline. - DOI - PubMed
    1. Liu X, Cruz Rivera S, Moher D, et al. Reporting guidelines for clinical trial reports for interventions involving artificial intelligence: the CONSORT-AI extension. Nat Med. 2020 Sep;26(9):1364–1374. doi: 10.1038/s41591-020-1034-x. doi. - DOI - PMC - PubMed
    1. Sittig DF, Singh H. A new sociotechnical model for studying health information technology in complex adaptive healthcare systems. Qual Saf Health Care. 2010 Oct;19 Suppl 3(Suppl 3):i68–74. doi: 10.1136/qshc.2010.042085. doi. Medline. - DOI - PMC - PubMed
    1. Sendak MP, Ratliff W, Sarro D, et al. Real-World Integration of a sepsis deep learning technology into routine clinical care: implementation study. JMIR Med Inform. 2020 Jul 15;8(7):e15182. doi: 10.2196/15182. doi. Medline. - DOI - PMC - PubMed

LinkOut - more resources