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Review
. 2025 Jul 1;21(5):989-994.
doi: 10.4103/jcrt.jcrt_1718_24. Epub 2025 Sep 26.

Theranostics and personalized radiopharmaceuticals

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Free article
Review

Theranostics and personalized radiopharmaceuticals

Sushant Sushant et al. J Cancer Res Ther. .
Free article

Abstract

Theranostics represents a novel approach in modern medicine, merging diagnostic and therapeutic methods into a unified framework tailored to individual patient needs. The current review explores the impact of personalized radiopharmaceuticals on the evolution of theranostics, particularly within oncology. The development of these specialized agents has revolutionized the way diseases are detected and treated, offering a more precise method that targets specific molecular features of tumors. By combining the ability to diagnose and treat with the same radiopharmaceutical, theranostics enables a more focused and efficient treatment pathway, minimizing adverse effects while enhancing therapeutic success. Personalized radiopharmaceuticals play a crucial role in this approach, offering the ability to monitor disease activity and therapeutic response in real time, thus providing critical insights for ongoing care. Integrating these advanced techniques into clinical practice is paving the way for more individualized cancer treatment, aligning with the broader goal of precision medicine. As this field advances, theranostics is expected to significantly improve patient outcomes and quality of life, marking a significant leap forward in personalized cancer care.

Keywords: Nanobrachytherapy; personalised medicine; personalised oncology; radiopharmaceuticals; theranostics.

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References

    1. Funkhouser J. Reinventing pharma:The theranostic revolution. Curr Drug Discov 2002;2:17–9.
    1. Collins FS, Varmus H. A new initiative on precision medicine. N Engl J Med 2015;372:793–5.
    1. Dhoundiyal S, Srivastava S, Kumar S, Singh G, Ashique S, Pal R, et al. Radiopharmaceuticals:Navigating the frontier of precision medicine and therapeutic innovation. Eur J Med Res 2024;29:26.
    1. Liu B, Zhou H, Tan L, Siu KT, Guan XY. Exploring treatment options in cancer:Tumor treatment strategies. Signal Transduct Target ther 2024;9:175.
    1. Barca C, Griessinger CM, Faust A, Depke D, Essler M, Windhorst AD, et al. Expanding theranostic radiopharmaceuticals for tumor diagnosis and therapy. Pharmaceuticals 2021;15:13.

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