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. 2025 Nov 10;43(32):3439-3445.
doi: 10.1200/JCO-25-01817. Epub 2025 Sep 26.

Bridging the Gap: The Evolving Landscape of CNS Management in Small Cell Lung Cancer: Prophylactic Cranial Irradiation in the Modern Era

Tafadzwa L Chaunzwa  1 , Salma K Jabbour  2 , Luke R G Pike  1 , Alissa J Cooper  3 , Narek Shaverdian  1 , Daniel Gomez  1
Affiliations

Bridging the Gap: The Evolving Landscape of CNS Management in Small Cell Lung Cancer: Prophylactic Cranial Irradiation in the Modern Era

Tafadzwa L Chaunzwa et al. J Clin Oncol. .
No abstract available

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Figures

Figure 1:
Figure 1:
Axial MRI slice showing the hippocampus (contoured in yellow) and the hippocampal avoidance region (5 mm margin expansion in purple). The prescription dose was 25 Gy in 10 daily fractions.
Figure 2:
Figure 2:
Axial and sagittal post-contrast T1-weighted MRI demonstrating a left anterior hippocampal metastasis.
Figure 3:
Figure 3:
Stereotactic radiosurgery plan targeting hippocampal brain metastasis with conformal dose distribution.
See this image and copyright information in PMC

References

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