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Randomized Controlled Trial
. 2025 Aug;16(4):1165-1171.
doi: 10.1055/a-2677-6012. Epub 2025 Sep 26.

Lessons Learned from Sepsis Microlearning Intervention

Affiliations
Randomized Controlled Trial

Lessons Learned from Sepsis Microlearning Intervention

Eduardo R Osegueda et al. Appl Clin Inform. 2025 Aug.

Abstract

Improving early recognition and treatment of sepsis is key to decreasing patient mortality. A large academic health system implemented several quality improvement initiatives, yet monthly compliance with sepsis best practices remained low.Develop and evaluate an electronic health record (EHR)-embedded microlearning intervention to address suboptimal adherence to sepsis care best practices.We conducted a randomized stepped-wedge trial of our microlearning intervention with randomization done at the nursing block level. Antibiotic delay and secondary outcomes extracted from the EHR were analyzed using mixed models to account for intracluster correlation.The microlearning intervention did not reduce antibiotic delay (mean difference = 0.71 hours; p = 0.49). Despite the alert firing over 30,000 times during the study period, the microlearning intervention was viewed only a total of 30 times.Our microlearning intervention did not improve sepsis care outcomes. We believe that although the content addressed key knowledge gaps, delivering the intervention through disruptive EHR alerts was not an accessible delivery channel to the nursing staff we targeted.

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Conflict of interest statement

None declared.

References

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