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. 2025 Nov 6;66(5):2500838.
doi: 10.1183/13993003.00838-2025. Print 2025 Nov.

Intravenous iron for the treatment of iron deficiency in adults with cystic fibrosis: a prospective observational cohort study

Nick P Talbot  1   2   3 , Matilda Downs  4   3 , Jennifer Cane  3 , Sandi Yen  5 , Goran Mohammad  4   6 , Alison Gates  2 , Joanna Snowball  2 , Magda Laskawiec-Szkonter  3 , Melissa Dobson  3 , Samira Lakhal-Littleton  4 , Jethro S Johnson  5 , Najib M Rahman  3   7 , Stephen Gerry  8 , Stephen J Chapman  2 , William G Flight  2
Affiliations

Intravenous iron for the treatment of iron deficiency in adults with cystic fibrosis: a prospective observational cohort study

Nick P Talbot et al. Eur Respir J. .

Abstract

In this pilot study in 20 adults with cystic fibrosis and iron deficiency, treatment with intravenous iron improved blood haemoglobin concentration and exercise capacity, without any adverse effect on clinical or laboratory markers of infection https://bit.ly/47eQKkR

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Conflict of interest statement

Conflict of interest: J. Snowball declares payment for a presentation and advisory board membership from Vertex pharmaceuticals. S. Lakhal-Littleton declares receipt of previous research funding from Vifor Pharma, personal honoraria for a lecture from Pharmacosmos, and consultancy fees from Disc Medicine and ScholarRock. W.G. Flight has been an employee and shareholder in GSK since 2022, but had no connection with GSK when this study was undertaken. The remaining authors have no potential conflicts of interest to disclose.

References

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