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Review
. 2025 Sep 2;12(9):1171.
doi: 10.3390/children12091171.

Transition of Cardiovascular Care in Survivors of Pediatric Cancer: From Preventive Strategies to Cardiac Follow-Up's Organization

Elena Bennati  1 , Alice Pozza  2 , Daniele Ciofi  3 , Sara Mantini  3 , Gaia Spaziani  1 , Alessia Tomberli  1 , Salvatore Angileri  3 , Iacopo Olivotto  1 , Silvia Favilli  1
Affiliations
Review

Transition of Cardiovascular Care in Survivors of Pediatric Cancer: From Preventive Strategies to Cardiac Follow-Up's Organization

Elena Bennati et al. Children (Basel). .

Abstract

Survival rates for childhood cancer patients (CCSs) have increased due to new treatments. Cardiovascular disease (CVD) is the leading cause of non-cancer morbidity and mortality in CCSs. CVD is the result of direct cardiovascular (CV) damage caused by cancer treatment and accelerated atherosclerosis. CCSs are at increased risk of metabolic syndrome, yet CV risk factors are underdiagnosed and undertreated in this population. A structured transition care plan plays a key role in promoting greater awareness of the importance of appropriate CV risk management and a healthy lifestyle. This narrative review aims to provide a comprehensive illustration of how transition programs face many barriers in daily practice and the need for a widespread transition culture.

Keywords: cardiotoxicity; childhood cancer survivors; follow-up; transition.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Continuum of CV transition care for CAYA cancer survivors from short- to long-term follow-up.
See this image and copyright information in PMC

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