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Review
. 2025 Sep 26:S1556-0864(25)02841-2.
doi: 10.1016/j.jtho.2025.09.1757. Online ahead of print.

International Thymic Malignancy Interest Group Standard Definitions, Policies, and Reporting Measures for Thymic Epithelial Tumors

Wentao Fang  1 , Frank Detterbeck  2 , Jeanne B Ackman  3 , Edith M Marom  4 , Anja C Roden  5 , Paolo Mendogni  6 , Mirella Marino  7 , Filippo Lococo  8 , Thierry J Molina  9 , Andreas Rimner  10 , Nicolas Girard  11 , Luigi Ventura  12 , Sara Ricciardi  13 , Ayten K Cangir  14 , Malgorzata Szolkowska  15 ; International Thymic Malignancy Interest Group Education Committee
Affiliations
Free article
Review

International Thymic Malignancy Interest Group Standard Definitions, Policies, and Reporting Measures for Thymic Epithelial Tumors

Wentao Fang et al. J Thorac Oncol. .
Free article

Abstract

Thymic epithelial tumors are rare diseases, with frequently indolent nature. A common language is essential for accurate communication in clinical management and research for this disease. The International Thymic Malignancy Interest Group updates its original set of standards for reporting outcome measures of clinical studies to facilitate comparison of results between studies and to promote collaborative research of the disease. These standards include international classification of tumor stage, long-term outcome measures with follow-up policy, standard definitions of recurrence and progression, and reporting measures for surgery and multimodality therapy. Implementing these renewed standards will support more accurate study designs, result reporting, and cross-specialty discussions and will facilitate multi-institutional and global collaboration.

Keywords: Follow-up; Outcomes; Recurrence; Thymic carcinoma; Thymoma.

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Conflict of interest statement

Disclosure Dr. Ackman reports receiving royalties from Elsevier and consulting fee from TPG Global and Tolerance Bio. Dr. Marom reports receiving honorarium for lectures from AstraZeneca, Boehringer Ingelheim, and Merck Sharp & Dohme. Dr. Roden reports receiving advisory board fees from AstraZeneca and Agilent. Dr. Rimner reports receiving institutional fees from AstraZeneca, Merck, Boehringer Ingelheim, Pfizer, and Varian Medical Systems; consulting fees from AstraZeneca, Merck, and MoreHealth; and honorarium for lecture from Boehringer Ingelheim. Dr. Szolkowska reports receiving honorarium for lectures from Amgen, Boehringer Ingelheim, 90Consulting, and Centrum Medyczne Kształcenia Podyplomoweg. The remaining authors declare no conflict of interest.

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