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. 2025 Oct;31(10):2051-2054.
doi: 10.3201/eid3110.250715.

Increased Rates of Purpureocillium lilacinum Mold among Laboratory Culture Results, United States

Increased Rates of Purpureocillium lilacinum Mold among Laboratory Culture Results, United States

Dallas J Smith et al. Emerg Infect Dis. 2025 Oct.

Abstract

Purpureocillium lilacinum, a common environmental mold and bionematicide, can cause human infections. At a major US commercial laboratory during March 2019-February 2025, P. lilacinum culture rates increased; rates were highest in the South Atlantic and Pacific states. Nonculture-based diagnostic tools such as microscopy may help identify and confirm clinical infection earlier.

Keywords: Purpureocillium; United States; fungi; hyalohyphomycosis; laboratories; mold.

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Figures

Figure
Figure
Rates of Purpureocillium lilacinum mold among laboratory culture results, United States. Graph shows P. lilacinum cultures per 100,000 fungal cultures by year and quarter during March 2019–February 2024.

References

    1. Sprute R, Salmanton-García J, Sal E, Malaj X, Ráčil Z, Ruiz de Alegría Puig C, et al. ; FungiScope® ECMM/ISHAM Working Group. Invasive infections with Purpureocillium lilacinum: clinical characteristics and outcome of 101 cases from FungiScope® and the literature. J Antimicrob Chemother. 2021;76:1593–603. 10.1093/jac/dkab039 - DOI - PMC - PubMed
    1. US Environmental Protection Agency. Registration decision for the new active ingredient Purpureocillium lilacinum strain PL11 [cited 2025 Apr 1]. https://www.regulations.gov/document/EPA-HQ-OPP-2016-0079-0013
    1. US Environmental Protection Agency. Paecilomyces species PC Codes 115002, 028826, and 115003 Interim registration review decision case number 6047 [cited 2025 Apr 1]. https://www.regulations.gov/document/EPA-HQ-OPP-2012-0403-0011
    1. Castelli MV, Alastruey-Izquierdo A, Cuesta I, Monzon A, Mellado E, Rodriguez-Tudela JL, et al. Susceptibility testing and molecular classification of Paecilomyces spp. Antimicrob Agents Chemother. 2008;52:2926–8. 10.1128/AAC.00538-08 - DOI - PMC - PubMed
    1. Centers for Disease Control and Prevention. Reportable fungal diseases by state [cited 2025 Sep 12]. https://www.cdc.gov/fungal/php/case-reporting/index.html

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