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. 2025 Sep 14:31:103027.
doi: 10.1016/j.fochx.2025.103027. eCollection 2025 Oct.

Guava (Psidium guajava): A brief overview of its therapeutic and health potential

Eman Butt  1 , Ammar B Altemimi  2   3 , Aqsa Younas  1 , Masood Sadiq Butt  4 , Maryam Jalal  1 , Maham Bhatty  1 , Gholamreza Abdi  5 , Rana Muhammad Aadil  1
Affiliations

Guava (Psidium guajava): A brief overview of its therapeutic and health potential

Eman Butt et al. Food Chem X. .

Abstract

Background: The guava (Psidium guajava) has long been valued for its variety of pharmacological characteristics. The plant has bioactive chemicals in its leaves, fruit, and bark, which enhance its potential for therapeutic use.

Objective: The goal of this review is to compile the most recent information on the pharmacological properties of guava, with an emphasis on its anti-inflammatory, anti-hypertensive, anti-obesity, antioxidant, antidiarrheal and antidiabetic properties as well as on its ability to treat dental diseases and increase haemoglobin levels in body.

Methods: To assess the potential health benefits derived from guava, a thorough review of it in vitro, and vivo clinical investigations was carried out.

Results: The main cause of guava's strong bioactivity is its flavonoids. Its application in the treatment of different diseases is supported by evidence. The medicinal potential of its inclusion in functional meals is encouraging.

Conclusion: The guava fruit has a wide range of therapeutic properties and is rich in nutrients. More human trials are needed to confirm efficacy, optimize dosage, and guarantee safety in long-term usage, even though preclinical research appears encouraging.

Keywords: Bioactive substances; Functional foods; Guava; Medicinal qualities; Psidium guajava.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Unlabelled Image
Graphical abstract
Fig. 1
Fig. 1
Botanical Classification of Guava.
Fig. 2
Fig. 2
Therapeutic properties of guava.
See this image and copyright information in PMC

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