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. 2025 Sep 29.
doi: 10.1007/s00134-025-08144-0. Online ahead of print.

Rethinking high PEEP strategies after IMPROVE-2?

Marcus J Schultz  1 , Lukas Gasteiger  2 , Galina A Dorland  3 , Ary Serpa Neto  4 , Guido Mazzinari  5
Affiliations

Rethinking high PEEP strategies after IMPROVE-2?

Marcus J Schultz et al. Intensive Care Med. .
No abstract available

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Conflict of interest statement

Declarations. Conflicts of interest: None.

References

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    1. Futier E, Constantin JM, Paugam-Burtz C et al (2013) A trial of intraoperative low-tidal-volume ventilation in abdominal surgery. N Engl J Med 369(5):428–437. https://doi.org/10.1056/NEJMoa1301082 - DOI - PubMed
    1. Hemmes SN, Gama de Abreu M, Pelosi P, Schultz MJ, PROVE Network Investigators for the Clinical Trial Network of the European Society of Anaesthesiology (2014) High versus low positive end-expiratory pressure during general anaesthesia for open abdominal surgery (PROVHILO trial): a multicentre randomised controlled trial. Lancet 384(9942):495–503. https://doi.org/10.1016/S0140-6736(14)60416-5 - DOI - PubMed
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    1. Ferrando C, Soro M, Unzueta C, iPROVE Network et al (2018) Individualised perioperative open-lung approach versus standard protective ventilation in patients undergoing one-lung ventilation for thoracoscopic surgery (iPROVE-OLV): an international, multicentre, randomised controlled trial. Lancet Respir Med 6(3):193–204. https://doi.org/10.1016/S2213-2600(18)30024-9 - DOI - PubMed

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