Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1971 Feb;8(2):335-44.

The origins of the immunoglobulins in the mucous secretions of cattle

C C Curtain, B L Clark, J H Dufty

The origins of the immunoglobulins in the mucous secretions of cattle

C C Curtain et al. Clin Exp Immunol. 1971 Feb.

Abstract

The predominating immunoglobulin in the mucous secretions of cattle appears to be IgG1. Radioactive tracer studies using 131I-labelled IgG1 and 125I-labelled IgG2 suggest that the larger part of this immunoglobulin is not derived from the plasma but is locally synthesized. Immunofluorescence studies indicate that this immunoglobulin is produced by lymphoid cells which can be observed in the lamina propria and at the base of the villi in the mucosae of the gut and respiratory system. There appears to be some degree of selectivity of transport of IgG1 from the plasma compared with IgG2, although this varies with the tissues.

PubMed Disclaimer

References

    1. J Exp Med. 1969 Feb 1;129(2):411-29 - PubMed
    1. Proc Soc Exp Biol Med. 1960 Jan;103:250-2 - PubMed
    1. Adv Immunol. 1968;9:1-96 - PubMed
    1. Immunology. 1966 Jun;10(6):499-506 - PubMed
    1. Biochem J. 1968 Apr;107(4):559-64 - PubMed

MeSH terms

LinkOut - more resources