Self-driving labs for biotechnology

Evan Collins^{1

2

3}, Robert Langer^{1

2

4

5

6}, Daniel G Anderson^{7

8

9

10}

Affiliations

¹ Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
² David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
³ Jameel Clinic, Massachusetts Institute of Technology, Cambridge, MA, USA.
⁴ Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
⁵ Harvard and MIT Division of Health Science and Technology, Massachusetts Institute of Technology, Cambridge, MA, USA.
⁶ Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA.
⁷ David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA. dgander@mit.edu.
⁸ Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA. dgander@mit.edu.
⁹ Harvard and MIT Division of Health Science and Technology, Massachusetts Institute of Technology, Cambridge, MA, USA. dgander@mit.edu.
¹⁰ Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA. dgander@mit.edu.

PMID: 41034460
DOI: 10.1038/s43588-025-00885-8

Self-driving labs for biotechnology

Evan Collins et al. Nat Comput Sci. 2025 Nov.

. 2025 Nov;5(11):976-979.

doi: 10.1038/s43588-025-00885-8.

Authors

Evan Collins^{1

2

3}, Robert Langer^{1

2

4

5

6}, Daniel G Anderson^{7

8

9

10}

Affiliations

¹ Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
² David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
³ Jameel Clinic, Massachusetts Institute of Technology, Cambridge, MA, USA.
⁴ Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
⁵ Harvard and MIT Division of Health Science and Technology, Massachusetts Institute of Technology, Cambridge, MA, USA.
⁶ Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA.
⁷ David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA. dgander@mit.edu.
⁸ Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA. dgander@mit.edu.
⁹ Harvard and MIT Division of Health Science and Technology, Massachusetts Institute of Technology, Cambridge, MA, USA. dgander@mit.edu.
¹⁰ Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA. dgander@mit.edu.

PMID: 41034460
DOI: 10.1038/s43588-025-00885-8

No abstract available

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Conflict of interest statement

Competing interests: D.G.A. receives research funding from Sanofi and is a founder of Orna Therapeutics, Soufflé Therapeutics and Combined Therapeutics. R.L. is a co-founder and former member of the board of directors of Moderna. He also serves on the board and has equity in Particles for Humanity. For a full list of entities with which R.L. is involved, compensated or uncompensated, see https://www.dropbox.com/scl/fi/ty2b7x8vyebid8ybcbeox/Rev-Langer-COI.pdf?rlkey=lko2srm1qjknm53ck9yns1dfj&e=1&dl=0 . E.C. has no competing interests to declare.

References

1. Abolhasani, M. & Kumacheva, E. Nat. Synth. 2, 483–492 (2023). - DOI
1. Martin, H. G. et al. Curr. Opin. Biotechnol. 79, 102881 (2023). - DOI
1. Rapp, J. T., Bremer, B. J. & Romero, P. A. Nat. Chem. Eng. 1, 97–107 (2024). - DOI
1. Coley, C. W. et al. Science 365, eaax1566 (2019). - DOI
1. Packer, M. S. & Liu, D. R. Nat. Rev. Genet. 16, 379–394 (2015). - DOI

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R33AI161805-05/U.S. Department of Health & Human Services | National Institutes of Health (NIH)

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Self-driving labs for biotechnology

Affiliations

Self-driving labs for biotechnology

Authors

Affiliations

Conflict of interest statement

References

Grants and funding

LinkOut - more resources

Full Text Sources