Author Correction: Prophylactic TNF blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy

Elisabeth Perez-Ruiz^{1

2

3

4

5}, Luna Minute^{1

2}, Itziar Otano^{1

2}, Maite Alvarez^{1

2}, Maria Carmen Ochoa^{1

2

6}, Virginia Belsue^{1

2}, Carlos de Andrea^{2

7}, Maria Esperanza Rodriguez-Ruiz^{1

3}, Jose Luis Perez-Gracia^{2

3

6}, Ivan Marquez-Rodas^{6

8}, Casilda Llacer⁹, Martina Alvarez^{5

10

11}, Vanesa de Luque^{5

10}, Carmen Molina^{1

2}, Alvaro Teijeira^{1

2

6}, Pedro Berraondo^#^{12

13

14}, Ignacio Melero^#^{15

16

17

18

19}

Affiliations

¹ Program of Immunology and Immunotherapy, Cima Universidad de Navarra, Pamplona, Spain.
² Navarra Institute for Health Research (IDISNA), Pamplona, Spain.
³ Department of Oncology, Clínica Universidad de Navarra, Pamplona, Spain.
⁴ Department of Oncology, Hospital Costa del Sol, Marbella, Spain.
⁵ Instituto de Investigación Biomédica de Málaga (IBIMA), Hospitales Universitarios Regional y Virgen de la Victoria, Málaga, Spain.
⁶ Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.
⁷ Department of Pathology, Clínica Universidad de Navarra, Pamplona, Spain.
⁸ Department of Oncology, Hospital General Universitario Gregorio Marañon, Madrid, Spain.
⁹ Department of Oncology, Hospital Universitario Virgen de la Victoria, Málaga, Spain.
¹⁰ Laboratorio de Biología Molecular del Cáncer, Centro de Investigaciones Médico-Sanitarias (CIMES), Universidad de Málaga, Málaga, Spain.
¹¹ Department of Pathology, Faculty of Medicine, Universidad de Málaga, Málaga, Spain.
¹² Program of Immunology and Immunotherapy, Cima Universidad de Navarra, Pamplona, Spain. pberraondol@unav.es.
¹³ Navarra Institute for Health Research (IDISNA), Pamplona, Spain. pberraondol@unav.es.
¹⁴ Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain. pberraondol@unav.es.
¹⁵ Program of Immunology and Immunotherapy, Cima Universidad de Navarra, Pamplona, Spain. imelero@unav.es.
¹⁶ Navarra Institute for Health Research (IDISNA), Pamplona, Spain. imelero@unav.es.
¹⁷ Department of Oncology, Clínica Universidad de Navarra, Pamplona, Spain. imelero@unav.es.
¹⁸ Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain. imelero@unav.es.
¹⁹ Department of Immunology and Immunotherapy, Clínica Universidad de Navarra, Pamplona, Spain. imelero@unav.es.

^# Contributed equally.

PMID: 41034590
DOI: 10.1038/s41586-025-09672-x

Published Erratum

Author Correction: Prophylactic TNF blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy

Elisabeth Perez-Ruiz et al. Nature. 2025 Oct.

. 2025 Oct;646(8087):E29-E30.

doi: 10.1038/s41586-025-09672-x.

Authors

Affiliations

¹ Program of Immunology and Immunotherapy, Cima Universidad de Navarra, Pamplona, Spain.
² Navarra Institute for Health Research (IDISNA), Pamplona, Spain.
³ Department of Oncology, Clínica Universidad de Navarra, Pamplona, Spain.
⁴ Department of Oncology, Hospital Costa del Sol, Marbella, Spain.
⁵ Instituto de Investigación Biomédica de Málaga (IBIMA), Hospitales Universitarios Regional y Virgen de la Victoria, Málaga, Spain.
⁶ Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.
⁷ Department of Pathology, Clínica Universidad de Navarra, Pamplona, Spain.
⁸ Department of Oncology, Hospital General Universitario Gregorio Marañon, Madrid, Spain.
⁹ Department of Oncology, Hospital Universitario Virgen de la Victoria, Málaga, Spain.
¹⁰ Laboratorio de Biología Molecular del Cáncer, Centro de Investigaciones Médico-Sanitarias (CIMES), Universidad de Málaga, Málaga, Spain.
¹¹ Department of Pathology, Faculty of Medicine, Universidad de Málaga, Málaga, Spain.
¹² Program of Immunology and Immunotherapy, Cima Universidad de Navarra, Pamplona, Spain. pberraondol@unav.es.
¹³ Navarra Institute for Health Research (IDISNA), Pamplona, Spain. pberraondol@unav.es.
¹⁴ Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain. pberraondol@unav.es.
¹⁵ Program of Immunology and Immunotherapy, Cima Universidad de Navarra, Pamplona, Spain. imelero@unav.es.
¹⁶ Navarra Institute for Health Research (IDISNA), Pamplona, Spain. imelero@unav.es.
¹⁷ Department of Oncology, Clínica Universidad de Navarra, Pamplona, Spain. imelero@unav.es.
¹⁸ Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain. imelero@unav.es.
¹⁹ Department of Immunology and Immunotherapy, Clínica Universidad de Navarra, Pamplona, Spain. imelero@unav.es.

^# Contributed equally.

PMID: 41034590
DOI: 10.1038/s41586-025-09672-x

No abstract available

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Erratum for

Prophylactic TNF blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy.
Perez-Ruiz E, Minute L, Otano I, Alvarez M, Ochoa MC, Belsue V, de Andrea C, Rodriguez-Ruiz ME, Perez-Gracia JL, Marquez-Rodas I, Llacer C, Alvarez M, de Luque V, Molina C, Teijeira A, Berraondo P, Melero I. Perez-Ruiz E, et al. Nature. 2019 May;569(7756):428-432. doi: 10.1038/s41586-019-1162-y. Epub 2019 May 1. Nature. 2019. PMID: 31043740

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Author Correction: Prophylactic TNF blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy

Affiliations

Author Correction: Prophylactic TNF blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy

Authors

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Erratum for

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