Contemporary Review of Overlap in Overactive Bladder Patients with Nephrolithiasis: Fluid Reduction in Overactive Bladder and Associated Factors Related To Nephrolithiasis
- PMID: 41037208
- DOI: 10.1007/s11934-025-01294-0
Contemporary Review of Overlap in Overactive Bladder Patients with Nephrolithiasis: Fluid Reduction in Overactive Bladder and Associated Factors Related To Nephrolithiasis
Abstract
Purpose of review: This contemporary review paper analyzes the impact of fluid reduction in overactive bladder and associated factors related to nephrolithiasis.
Recent findings: Historically, overactive bladder and nephrolithiasis have been considered separate urologic pathologies. However, patients with OAB symptoms often restrict fluid intake to prevent episodes of urinary incontinence with resultant supersaturated urine, which precipitates nephrolithiasis formation. Coexistent pathologies promote the relationship between overactive bladder and nephrolithiasis, including urinary tract infection-related urolithiasis, bladder stones secondary to voiding dysfunction, and genitourinary syndrome of menopause. Overactive bladder and nephrolithiasis are profoundly impacted by fluid intake. The approach to overactive bladder should aim to optimize quality of life primarily by managing symptoms to avoid patient-imposed fluid intake restriction. By promoting patient confidence to consume the recommended daily fluid intake, nephrolithiasis formation risk is reduced. Eradication of other coexistent pathologies will further reduce overactive bladder symptoms and decrease stone formation.
Keywords: Fluid restriction; Nephrolithiasis; Overactive bladder.
© 2025. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
Conflict of interest statement
Declarations. Competing interests: The authors declare no competing interests. Human/Animal Studies Informed Consent Statement: This article does not contain any studies with human or animal subjects performed by any of the authors.
References
-
- Park J, Lee H, Kim Y, Norton C, Woodward S, Lee S. Effectiveness of fluid and caffeine modifications on symptoms in adults with overactive bladder: A systematic review. Int Neurourol J. 2023;27(1):23–35. https://doi.org/10.5213/inj.2346014.007 . Epub 2023 Mar 31. - DOI - PubMed - PMC
-
- Latini JM, Giannantoni A. Pharmacotherapy of overactive bladder: epidemiology and pathophysiology of overactive bladder. Expert Opin Pharmacother. 2011;12(7):1017–27. https://doi.org/10.1517/14656566.2011.554396 . - DOI - PubMed
-
- Tamborino F, Cicchetti R, Mascitti M, Litterio G, Orsini A, Ferretti S, et al. Pathophysiology and main molecular mechanisms of urinary stone formation and recurrence. Int J Mol Sci. 2024;25(5):3075. https://doi.org/10.3390/ijms25053075 . - DOI - PubMed - PMC
-
- Alibrahim H, et al. Kidney stone prevalence among US population: updated Estimation from Nhanes data set. JU Open Plus. 2024;2(11). https://doi.org/10.1097/ju9.0000000000000217 .
-
- Jebir RM, Mustafa YF. Kidney stones: natural remedies and lifestyle modifications to alleviate their burden. Int Urol Nephrol. 2024;56(3):1025–33. https://doi.org/10.1007/s11255-023-03764-1 . Epub 2023 Aug 29. - DOI - PubMed
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