Standardized Indirect Immunofluorescence-Based Detection of Dermal-Binding Autoantibodies in Pemphigoid Diseases: a prospective international multicentre study

Sabrina Patzelt¹, Rengin Melis Engin¹, Kossara Drenovska², Charlotte Kiehne^{1

3}, Christian Probst⁴, Lars Komorowski⁴, Swantje Mindorf⁴, Maryam Danrshpazhooh⁵, Soo-Chan Kim⁶, Francesca Farnetani⁷, Cristina Vaschieri⁷, Raghavendra Rao⁸, Angelo Valerio Marzano^{9

10}, Marian Dmochowski¹¹, Aikaterini Patsatsi¹², Dedee Murrell¹³, Johannes S Kern¹⁴, Hilayda Karakok Kisla¹⁵, Eli Sprecher¹⁶, Dipankar De¹⁷, Giovanni Di Zenzo¹⁸, Luca Borradori¹⁹, Hana Jedlickova²⁰, Xuejun Zhu²¹, Enno Schmidt^{1

3}, Stephanie Goletz¹

Affiliations

¹ Lübeck Institute of Experimental Dermatology, University of Lübeck, Lübeck, Germany.
² Department of Dermatology and Venereology, Medical University, Sofia, Bulgaria.
³ Department of Dermatology, Universitätsklinik Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.
⁴ Institute of Experimental Immunology, EUROIMMUN AG, Lübeck, Germany.
⁵ Autoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran.
⁶ Department of Dermatology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
⁷ Dermatology Department, University of Modena and Reggio Emilia, Modena, Italy.
⁸ Department of Dermatology, Venereology and Leprosy, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Karnataka, India.
⁹ Dermatology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
¹⁰ Department of Physiopathology and Transplantation, Università degli Studi di Milano, Milan, Italy.
¹¹ Autoimmune Blistering Dermatoses Section, Department of Dermatology, Poznan University of Medical Sciences, Poznan, Poland.
¹² 2nd Department of Dermatology, Autoimmune Bullous Diseases Unit, Aristotle University School of Medicine, Papageorgiou General Hospital, Thessaloniki, Greece.
¹³ Department of Dermatology, St George Hospital, University of New South Wales, Sydney, New South Wales, Australia.
¹⁴ Department of Dermatology, Alfred Hospital, Central Clinical School, Monash University, Melbourne, Australia.
¹⁵ Department of Dermatology and Venereology, Ankara University Faculty of Medicine, Ankara, Turkey.
¹⁶ Division of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
¹⁷ Department of Dermatology, PGIMER, Chandigarh, India.
¹⁸ Molecular and Cell Biology laboratory, Istituto Dermatico dell'Immacolata (IDI)-IRCCS, Rome, Italy.
¹⁹ Department of Dermatology, University of Bern, Inselspital, Berne, Switzerland.
²⁰ Department of Dermatovenereology, Masaryk University, St. Anna Hospital, Brno, Czech Republic.
²¹ Department of Dermatology, Peking University First Hospital, Beijing, China.

PMID: 41037486
DOI: 10.1093/bjd/ljaf385

Standardized Indirect Immunofluorescence-Based Detection of Dermal-Binding Autoantibodies in Pemphigoid Diseases: a prospective international multicentre study

Sabrina Patzelt et al. Br J Dermatol. 2025.

. 2025 Oct 1:ljaf385.

doi: 10.1093/bjd/ljaf385. Online ahead of print.

Authors

Affiliations

¹ Lübeck Institute of Experimental Dermatology, University of Lübeck, Lübeck, Germany.
² Department of Dermatology and Venereology, Medical University, Sofia, Bulgaria.
³ Department of Dermatology, Universitätsklinik Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.
⁴ Institute of Experimental Immunology, EUROIMMUN AG, Lübeck, Germany.
⁵ Autoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran.
⁶ Department of Dermatology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
⁷ Dermatology Department, University of Modena and Reggio Emilia, Modena, Italy.
⁸ Department of Dermatology, Venereology and Leprosy, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Karnataka, India.
⁹ Dermatology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
¹⁰ Department of Physiopathology and Transplantation, Università degli Studi di Milano, Milan, Italy.
¹¹ Autoimmune Blistering Dermatoses Section, Department of Dermatology, Poznan University of Medical Sciences, Poznan, Poland.
¹² 2nd Department of Dermatology, Autoimmune Bullous Diseases Unit, Aristotle University School of Medicine, Papageorgiou General Hospital, Thessaloniki, Greece.
¹³ Department of Dermatology, St George Hospital, University of New South Wales, Sydney, New South Wales, Australia.
¹⁴ Department of Dermatology, Alfred Hospital, Central Clinical School, Monash University, Melbourne, Australia.
¹⁵ Department of Dermatology and Venereology, Ankara University Faculty of Medicine, Ankara, Turkey.
¹⁶ Division of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
¹⁷ Department of Dermatology, PGIMER, Chandigarh, India.
¹⁸ Molecular and Cell Biology laboratory, Istituto Dermatico dell'Immacolata (IDI)-IRCCS, Rome, Italy.
¹⁹ Department of Dermatology, University of Bern, Inselspital, Berne, Switzerland.
²⁰ Department of Dermatovenereology, Masaryk University, St. Anna Hospital, Brno, Czech Republic.
²¹ Department of Dermatology, Peking University First Hospital, Beijing, China.

PMID: 41037486
DOI: 10.1093/bjd/ljaf385

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Standardized Indirect Immunofluorescence-Based Detection of Dermal-Binding Autoantibodies in Pemphigoid Diseases: a prospective international multicentre study

Affiliations

Standardized Indirect Immunofluorescence-Based Detection of Dermal-Binding Autoantibodies in Pemphigoid Diseases: a prospective international multicentre study

Authors

Affiliations

LinkOut - more resources

Full Text Sources